Adenofibroma of the uterine cervix coexistent with endometriosis

Chu IL, I-Lin Chu, Chi‐Long Chen, Chen CL, Chi-Long Chen, Chun-Sen Hsu, Hsu CS
Taiwanese journal of obstetrics & gynecology · 2012 · vol. 51(2) , pp. 285–288 · doi:10.1016/j.tjog.2012.04.022 · PMID:22795111 · W1975535838
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This report describes a 52-year-old woman with a recurrent cervical adenofibroma coexisting with endometriosis, which presented as a polypoid mass causing vaginal spotting.

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Abstract

Adenofibromas are rare tumors of the female genital tract, first reported by Abell in 1971 [1], and most arise from the uterus or cervix. Cervical adenofibromas are most commonly seen in perior postmenopausal women, and typically present with abnormal vaginal bleeding [1]. Grossly, the tumor usually appears as a polypoid mass at cervix [1,2]. Adenofibromas are composed of an admixture of benign epithelial and mesenchymal elements, and must be differentiated from adenosarcoma, adenomyomas, and carcinosarcoma [2e4]. In rare instances, adenofibromas have been associated with endometriosis [5]. We herein report a case of a 52-year-old woman with a recurrent adenofibroma of the cervix coexistent with endometriosis. A 52-year-old woman presented with vaginal spotting. Her last menstrual period was approximately 1 month prior, and her history was significant only for endometriosis. Pelvic examination revealed a polyploid mass at the cervix. Ultrasonography revealed a normal uterus and adnexa. Pelvic magnetic resonance imaging (MRI) revealed a focal mass at the posterior lip of the cervix extending to the vagina, with heterogeneous enhancement. Routine hematological and biochemical studies were within normal limits; however, serum CA-125 level (normal values range from 0 to 35 U/mL) was slightly elevated (46 U/mL). Transvaginal biopsy of the mass was performed, and histopathological examination was consistent with an adenomyomatous polyp. The mass was subsequently excised (Table 1). Two years later, the patient again complained of vaginal spotting, and examination revealed a polyploid mass at the site of the previous lesion. Transvaginal ultrasound revealed two small masses near the cervix, and MRI showed a soft tissue mass at the posterior aspect of the lower uterus/cervix. Excision of the mass was performed, and the histopathological

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Condition tags

endometriosis

MeSH descriptors

Adenofibroma Adenofibroma Endometriosis Neoplasm Recurrence, Local Uterine Cervical Neoplasms Uterine Cervical Neoplasms Adenofibroma Adenofibroma Endometriosis Female Humans Hysterectomy Middle Aged Neoplasm Recurrence, Local Neoplasm Recurrence, Local Uterine Cervical Neoplasms Uterine Cervical Neoplasms

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