Oxygen free radicals and pelvic adhesion formation: I. Blocking oxygen free radical toxicity to prevent adhesion formation in an endometriosis model

International journal of fertility · 1991 · vol. 36(1) , pp. 39–42 · PMID:1672675 · W173679487
Lab / animal OA: closed CC0 ⤵ 33 in-corpus citations
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This study investigated blocking oxygen free radical toxicity with superoxide dismutase and catalase to prevent adhesion formation in a rabbit model of endometriosis.

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Abstract

Intraperitoneal superoxide dismutase (SOD) and catalase were used to block the toxic effects of superoxide anion (O2) and hydrogen peroxide (H2O2), associated with the production of endometriosis and inflammation in a rabbit model. In a two-part animal study, the combined instillation of SOD and catalase significantly reduced the formation of intraperitoneal adhesions at endometriosis sites.

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Condition tags

endometriosis

MeSH descriptors

Catalase Hydrogen Peroxide Oxygen Peritoneal Diseases Superoxide Dismutase Animals Animals Catalase Catalase Endometriosis Endometriosis Endometriosis Endometriosis Free Radicals Free Radicals Hydrogen Peroxide Hydrogen Peroxide Oxygen Oxygen Pelvic Neoplasms

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

Cited by (33)

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