Oxygen free radicals and pelvic adhesion formation: I. Blocking oxygen free radical toxicity to prevent adhesion formation in an endometriosis model.

International journal of fertility · 1991 · vol. 36(1) , pp. 39–42 · PMID:1672675 · W173679487
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AI-generated summary by claude@2026-06, 2026-06-07

This study investigated blocking oxygen free radical toxicity with superoxide dismutase and catalase to prevent adhesion formation in a rabbit model of endometriosis.

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Abstract

Intraperitoneal superoxide dismutase (SOD) and catalase were used to block the toxic effects of superoxide anion (O2) and hydrogen peroxide (H2O2), associated with the production of endometriosis and inflammation in a rabbit model. In a two-part animal study, the combined instillation of SOD and catalase significantly reduced the formation of intraperitoneal adhesions at endometriosis sites.

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Condition tags

endometriosis

MeSH descriptors

Catalase Hydrogen Peroxide Oxygen Peritoneal Diseases Superoxide Dismutase Animals Catalase Endometriosis Endometriosis Endometriosis Free Radicals Hydrogen Peroxide Oxygen Pelvic Neoplasms Pelvic Neoplasms Pelvic Neoplasms Peritoneal Diseases Peritoneal Diseases Peritoneal Diseases Rabbits

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (33)

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