Oxygen free radicals and pelvic adhesion formation: I. Blocking oxygen free radical toxicity to prevent adhesion formation in an endometriosis model.
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This study investigated blocking oxygen free radical toxicity with superoxide dismutase and catalase to prevent adhesion formation in a rabbit model of endometriosis.
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Abstract
Intraperitoneal superoxide dismutase (SOD) and catalase were used to block the toxic effects of superoxide anion (O2) and hydrogen peroxide (H2O2), associated with the production of endometriosis and inflammation in a rabbit model. In a two-part animal study, the combined instillation of SOD and catalase significantly reduced the formation of intraperitoneal adhesions at endometriosis sites.
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Cited by (33)
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- Biomarkers for the Noninvasive Diagnosis of Endometriosis: State of the Art and Future Perspectives 2020
- The effects of thalidomide in a rat model of surgically-induced endometriosis 2015
- Prevention of Endometriosis 2014
- Mitochondrial displacement loop alterations are associated with endometriosis 2013
- Increased levels of oxidative stress markers in the peritoneal fluid of women with endometriosis 2013
- Effects of amifostine on endometriosis, comparison with N-acetyl cysteine, and leuprolide as a new treatment alternative: a randomized controlled trial 2013
- Mitochondrial NADH:ubiquinone oxidoreductase alterations are associated with endometriosis 2013
- Melatonin treatment results in regression of endometriotic lesions in an ooferectomized rat endometriosis model 2013
- Melatonin treatment results in regression of endometriotic lesions in an ooferectomized rat endometriosis model Melatonin tedavisi ooferektomize siçanlar endometriozis modelinde endometriotik odaklarda gerilemeye yol açar 2013
- Mitochondrial Genome Variations in Advanced Stage Endometriosis: A Study in South Indian Population 2012
- Endometriosis and Oxidative Stress 2012
- Female Infertility and Antioxidants 2010
- Peritoneal adhesions in human and veterinary medicine: from pathogenesis to therapy. A review 2010
- Leptin and antioxidant profile in infertile women with endometriosis 2010
- Newer treatment modalities in endometriosis: systematic review 2009
- SIGNIFICANCE OF OXIDATIVE STRESS IN HUMAN REPRODUCTION 2009
- The role of the oxidative-stress in the endometriosis-related infertility 2009
- Role of melatonin in regulating matrix metalloproteinase‐9 via tissue inhibitors of metalloproteinase‐1 during protection against endometriosis 2008
- Comparative proteomic analysis of human adenomyosis using two-dimensional gel electrophoresis and mass spectrometry 2007
- Regression of endometrial explants in a rat model of endometriosis treated with melatonin 2007
- Role of oxidative stress in endometriosis 2006
- Female Infertility and Free Radicals: Potential Role in Adhesions and Endometriosis 2006
- Oxidative stress and endometriosis 2005
- Effects of oxidants and antioxidants on proliferation of endometrial stromal cells 2004
- Oxidative stress may be a piece in the endometriosis puzzle 2003
- Investigation of glutathione concentrations in peritoneal fluid from women with and without endometriosis 2003
- Nuevos conceptos en la patogénesis y tratamiento de la endometrosis asociada a dolor 2003
- Oxidative stress and peritoneal endometriosis 2002
- Levels of lipid perioxides and superoxide dismutase in peritoneal fluid of patients with endometriosis 2001
- Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis 1997
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