CA-125 levels in endometriosis

Phillip E. Patton, Patton PE, P E Patton, Charles S. Field, C S Field, Field CS, R W Harms, Harms RW, Roger W. Harms, C B Coulam, Carolyn B. Coulam, Coulam CB
Fertility and sterility · 1986 · vol. 45(6) , pp. 770–773 · doi:10.1016/s0015-0282(16)49390-8 · PMID:2423378 · W38360880
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This paper investigates the role of CA-125 levels in the context of endometriosis, exploring its association with disease severity and patient symptoms.

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Abstract

CA-125 is a cellular antigen detected in many patients with ovarian cancer, but it has also been detected in patients with endometriosis. Preoperative CA-125 levels were drawn from 113 patients before they underwent laparoscopy. Patients were categorized into diagnostic groups on the basis of pathologic findings. CA-125 levels in patients with evidence of intraabdominal adhesions were not statistically different from those in patients with normal pelvic anatomy. However, patients with advanced endometriosis had significantly elevated levels of CA-125 when compared with patients with normal pelvic anatomy (P less than 0.05). The clinical and immunologic implications of elevated CA-125 levels in patients with advanced endometriosis are discussed.

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Condition tags

endometriosis

MeSH descriptors

Antigens, Neoplasm Antigens, Surface Endometriosis Epitopes Adolescent Adult Antigens, Neoplasm Antigens, Surface Antigens, Tumor-Associated, Carbohydrate Endometriosis Endometriosis Epitopes Female Genital Diseases, Female Genital Diseases, Female Humans Middle Aged Radioimmunoassay Tissue Adhesions Tissue Adhesions

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (39)

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License: CC0 · commercial use OK