Ovarian cancer in a woman previously diagnosed with endometriosis and an extremely high serum CA-125 level.
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A woman initially diagnosed with endometriosis and an extremely high CA-125 later developed extensive ovarian clear-cell carcinoma with metastases, proving fatal.
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Abstract
PURPOSE: Follow-up of a woman with a serum CA-125 level > 1000 U/mL where laparoscopy only found endometriosis. METHODS: Case report-- re-evaluation several years later. RESULTS: Extensive clear-cell carcinoma of ovary with metastases leading to death. CONCLUSION: This case suggests that bilateral oophorectomy should be performed in women not desiring any more children if the serum CA- 125 level is very high even if only endometriosis is found initially.
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Cited by (5)
- Associations between Estrogen Receptor Gene Polymorphisms and Endometriosis 2013
- Identification of anti-syntaxin 5 autoantibody as a novel serum marker of endometriosis 2011
- Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer 2009
- Identification of anti‐α‐enolase autoantibody as a novel serum marker for endometriosis 2009
- CA-125 as a biomarker for malignant transformation of endometriosis 2009
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- europepmc
- last seen: 2026-06-13T06:22:48.782012+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:13:19.284922+00:00
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