Vascular endothelial growth factor (VEGF) and ovarian endometriosis: correlation between VEGF serum levels, VEGF cellular expression, and pelvic pain

García-Manero M, Manuel García-Manero, Alcazar JL, Juan Luis Alcazar, Juan Luis Alcázar, Gemma Toledo
Fertility and sterility · 2007 · vol. 88(2) , pp. 513–515 · doi:10.1016/j.fertnstert.2006.11.117 · PMID:17296185 · W2025321452
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This paper investigated the relationship between VEGF serum levels, VEGF cellular expression in the endometrium, and pelvic pain in women with ovarian endometriosis.

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Abstract

Vascular endothelial growth factor (VEGF) serum levels and VEGF and cellular expression were prospectively analyzed in 60 patients (group A consisted of asymptomatic patients or patients presenting mild dysmenorrhea; 30 women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among VEGF serum levels, VEGF cellular expression, and pelvic pain. No differences were found in VEGF serum levels and VEGF cellular expression between both groups. Therefore, we conclude that pain symptoms in ovarian endometriosis are not correlated with VEGF serum levels and VEGF cellular expression.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Endometriosis Ovarian Diseases Ovarian Diseases Pelvic Pain Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor A Adult Endometriosis Endometriosis Female Humans Ovarian Cysts Ovarian Cysts Ovarian Diseases Ovarian Diseases Pelvic Pain Pelvic Pain Pelvic Pain Prospective Studies

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (22)

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