Interleukin-8 serum levels do not correlate with pelvic pain in patients with ovarian endometriomas

Manero MG, Manuel García Manero, Alcazar JL, Juan Luis Alcazar, Juan Luis Alcázar
Fertility and sterility · 2009 · vol. 94(2) , pp. 450–452 · doi:10.1016/j.fertnstert.2009.03.074 · PMID:19423093 · W2042764340
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This study investigated the relationship between serum levels of interleukin-8 and pelvic pain in patients diagnosed with ovarian endometriomas, finding no significant correlation.

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Abstract

ObjectiveTo determine whether interleukin-8 (IL-8) serum levels are correlated with pelvic pain in patients with ovarian endometriomas.DesignProspective study.SettingTertiary-care university hospital.Patient(s)Interleukin-8 serum levels were prospectively analyzed in 51 patients (group A, asymptomatic patients or patients with mild dysmenorrhea; group B, severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists between IL-8 serum levels and pelvic pain.Intervention(s)Interleukin-8 serum levels determination.Main outcome measure(s)Interleukin-8 serum levels and pelvic pain.Result(s)From 56 patients, five cases were ultimately excluded because the histologic diagnosis was not cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean (+/-SD) IL-8 serum levels in group A were 6.41 +/- 12.17 pg/mL and in group B were 6.52 +/- 8.73 pg/mL.Conclusion(s)Pain symptoms in ovarian endometriosis is not correlated with IL-8 serum levels.

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Condition tags

dysmenorrheaendometriosischronic_pelvic_pain

MeSH descriptors

Biomarkers Endometriosis Endometriosis Interleukin-8 Pelvic Pain Pelvic Pain Adult Biomarkers Chronic Disease Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Female Humans Interleukin-8 Ovarian Cysts Ovarian Cysts Ovarian Cysts Pelvic Pain

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References (21)

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