Adverse pregnancy outcomes associated with adenomyosis with uterine enlargement

Aya Mochimaru, Mochimaru A, Shigeru Aoki, Oba MS, Mari S. Oba, Kurasawa K, Kentaro Kurasawa, Takahashi T, Tsuneo Takahashi, Tetsu Takahashi, Fumiki Hirahara, Hirahara F
Journal of Obstetrics and Gynaecology Research · 2014 · vol. 41(4) , pp. 529–533 · doi:10.1111/jog.12604 · PMID:25363157 · W2133603715
Observational OA: closed CC0 ⤵ 73 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

Women with adenomyosis experienced higher rates of preterm delivery, small-for-gestational age infants, fetal malpresentation, and cesarean delivery compared to women without uterine abnormalities.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

AIM: The aim of this study was to elucidate the risk of poor pregnancy outcomes in women with adenomyosis by comparing their outcomes to those of women without uterine abnormalities. MATERIAL AND METHODS: The subjects were 36 women diagnosed with adenomyosis before pregnancy who were managed at a tertiary care center between January 2002 and December 2012. Our hospital database was retrospectively reviewed to identify pregnancy outcomes associated with adenomyosis. The control group consisted of 144 women without uterine abnormalities who gave birth during the same period and whose age at delivery was adjusted by applying propensity scores. Pregnancy outcomes were compared between the adenomyosis and control groups. The main outcomes were gestational age at delivery, preterm delivery, preterm premature rupture of membranes, fetal malpresentation, cesarean delivery, small-for-gestational age, 5-min Apgar score < 7, umbilical arterial pH < 7.1, and neonatal intensive care unit admission. The data are presented as medians (range) or frequencies (percentage). RESULTS: The adenomyosis group had significantly higher rates of preterm delivery (41.7% vs 12.5%), preterm premature rupture of membranes (19.4% vs 4.2%), small-for-gestational age (33.3% vs 10.4%), fetal malpresentation (27.8% vs 8.3%), and cesarean delivery (58.3% vs 24.3%), as compared with the control group. No significant differences were observed in 5-min Apgar score < 7 or umbilical arterial pH < 7.1 between the two groups. CONCLUSIONS: Pregnancies in women with adenomyosis were associated with a higher preterm delivery rate and more frequent occurrences of fetal growth restriction and fetal malpresentation, such that both pregnancy and delivery outcomes were poor.

My notes (saved in your browser only)

Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Premature Birth Premature Rupture of Fetal Membranes Uterus Adenomyosis Adenomyosis Adenomyosis Adult Adult Delivery, Obstetric Delivery, Obstetric Female Female Gestational Age Gestational Age Humans Humans Infant, Newborn Infant, Newborn Pregnancy

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (21)

Cited by (50)

Source provenance

europepmc
last seen: 2026-10-13T06:10:10.580696+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:14:34.357477+00:00
License: CC0 · commercial use OK