Use of a levonorgestrel-releasing intrauterine device in the treatment of rectovaginal endometriosis

L Fedele, Luigi Fedele, S Bianchi, Stefano Bianchi, G. Zanconato, Zanconato G, Giovanni Zanconato, Portuese A, A Portuese, Antonella Portuese, R Raffaelli, Ricciarda Raffaelli
Fertility and sterility · 2001 · vol. 75(3) , pp. 485–488 · doi:10.1016/s0015-0282(00)01759-3 · PMID:11239528 · W2144527270
Non-randomised trial OA: bronze CC0 ⤵ 210 in-corpus citations
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This study investigated the efficacy of a levonorgestrel-releasing intrauterine device for treating rectovaginal endometriosis.

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Abstract

OBJECTIVE: To evaluate the effectiveness of a levonorgestrel-releasing IUD as therapy for endometriosis of the rectovaginal septum. DESIGN: Prospective therapeutic non-randomized, self-controlled clinical trial analyzing changes in pain symptoms and size of lesions induced by the levonorgestrel-releasing IUD over 12 months. SETTING: Tertiary referral center for treatment of deep endometriosis. PATIENT(S): Eleven symptomatic patients with rectovaginal endometriosis. INTERVENTION(S): A levonorgestrel-releasing IUD was inserted and maintained for 12 months. MAIN OUTCOME MEASURE(S): Severity of dysmenorrhea, pelvic pain, and deep dyspareunia were assessed before insertion of the IUD and throughout treatment. The size of rectovaginal endometriotic lesions were evaluated by using transrectal and transvaginal ultrasonography. RESULT(S): Dysmenorrhea, pelvic pain, and deep dyspareunia greatly improved and the size of the endometriotic lesions was significantly reduced by treatment. CONCLUSION(S): Insertion of a levonorgestrel-releasing IUD alleviates pain and reduces the size of lesions in patients with endometriosis of the rectovaginal septum.

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Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_painbowel_endometriosis

MeSH descriptors

Endometriosis Levonorgestrel Rectal Diseases Vaginal Diseases Adult Adult Dysmenorrhea Dysmenorrhea Dysmenorrhea Dyspareunia Dyspareunia Dyspareunia Endometriosis Endometriosis Endometriosis Female Female Humans Humans Intrauterine Devices

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (14)

Cited by (50)

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License: CC0 · commercial use OK