Association between endometriosis and polymorphisms in endostatin and vascular endothelial growth factor and their serum levels in Korean women

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AI-generated summary by claude@2026-06, 2026-06-08

This study investigated the association between endometriosis and specific genetic variations and serum levels of endostatin and vascular endothelial growth factor in Korean women.

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Abstract

The aim of present study was to evaluate the relationship between endometriosis and polymorphisms in the endostatin and vascular endothelial growth factor (VEGF) genes, and their levels in serum in a Korean population. Serum endostatin levels (but not VEGF levels) were negatively correlated with the development of endometriosis, specifically in early-stage endometriosis patients, compared with women without endometriosis, but endometriosis was not associated with the endostatin G(4349)A and VEGF C(936)T polymorphisms.

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Condition tags

endometriosis

MeSH descriptors

Asian People Endometriosis Endometriosis Endostatins Endostatins Polymorphism, Single Nucleotide Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor A Adult Asian People Case-Control Studies Endometriosis Endostatins Female Gene Frequency Genetic Predisposition to Disease Humans Korea Risk Assessment Risk Factors

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References (16)

Cited by (31)

Source provenance

europepmc
last seen: 2026-08-07T06:07:27.085738+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:15:00.519696+00:00
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