Animal model of uterine adenomyosis: Is prolactin a potent inducer of adenomyosis in mice?

T Mori, Mori T, Takao Mori, Tippawan Singtripop, T Singtripop, Singtripop T, S Kawashima, Seiichiro Kawashima, Kawashima S
American journal of obstetrics and gynecology · 1991 · vol. 165(1) , pp. 232–234 · doi:10.1016/0002-9378(91)90258-s · PMID:1853904 · W1967036278
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This study investigates whether prolactin is a potent inducer of uterine adenomyosis in a mouse model.

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Abstract

Uterine adenomyosis is a benign lesion but a serious disease for women, because the symptoms are characterized by abnormal bleeding, pain, cramps, and sterility. Thus elucidation of the mechanisms involved in the development of the disease would contribute to improved management and treatment and prophylaxis of this lesion. A mouse model, in which ectopic pituitary isografting is associated with an increase in the plasma level of prolactin, is useful for a rapid and frequent induction of uterine adenomyosis and can be used to study the origin of this lesion.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Prolactin Animals Disease Models, Animal Endometriosis Endometriosis Endometriosis Mice Microscopy, Electron

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (54)

Cited by (40)

Source provenance

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License: CC0 · commercial use OK