Kinderwunsch und Schwangerschaft bei Endometriose

In: Gynäkologische Endokrinologie · 2016 · vol. 14(1) , pp. 21–25 · doi:10.1007/s10304-015-0052-0 · W2279265915
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Surgical endometriosis removal may improve spontaneous conception, and current literature suggests against routine surgical treatment before IVF/ICSI, though pregnancy risks exist with certain endometriosis types.

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Die Übersichtsarbeit untersucht Ursachen und Behandlungsoptionen bei Patientinnen mit Endometriose und Kinderwunsch sowie die Folgen der Endometriose für Schwangerschaften, indem die aktuelle Literatur zu diesem Themenfeld zusammengefasst wird. Als zentrales Ergebnis wird beschrieben, dass eine operative Endometriosesanierung die Wahrscheinlichkeit einer spontanen Konzeption erhöhen kann, während Endometriome nicht automatisch vor IVF oder ICSI operativ behandelt werden sollen. Für die Frage nach dem Einfluss verschiedener Formen wird berichtet, dass ein gesicherter Effekt der ovarillen, tief infiltrierenden oder rektalen Endometriose auf die Schwangerschaftswahrscheinlichkeit nach IVF/ICSI nicht belegt ist, diese Befunde jedoch Risiken während der Schwangerschaft bergen können. Dieser Beitrag behandelt auch den gebärfähigen Kontext mit Bezug auf Adenomyose, thematisiert aber die Kernaussage primär zur Endometriose. This paper is centrally about endometriosis — it focuses on infertility and pregnancy outcomes in the context of endometriosis and associated surgical and fertility-treatment considerations.

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Material

und Methoden In dieser Übersichtsarbeit wird die aktuelle Literatur zum Thema zusammengefasst. Ergebnisse und Schlussfolgerung Eine operative Endometriosesanierung kann die Wahrscheinlichkeit einer spontanen Konzeption erhöhen. Endometriome sollten nicht mehr automatisch vor einem Versuch der In-vitro-Fertilisation (IVF) oder intrazytoplasmatischen Spermieninjektion (ICSI) operativ behandelt werden. Auch wenn fraglich ist, ob die ovarielle, die tief infiltrierende oder auch die Rektumendometriose die Wahrscheinlichkeit einer Schwangerschaft nach IVF/ICSI-Behandlung beeinflusst, bergen diese Faktoren Risiken während einer Schwangerschaft.

Abstract

Background Endometriosis is the second most frequent benign gynecological disease in women during the fertile period after uterine myoma. Endometriosis is frequently associated with infertility.

Objective

The aim of this article is to provide insights into the causes and treatment options for patients with endometriosis and a desire for children and to discuss the influence of endometriosis on pregnancy.

Material and methods

This article gives a review and summary of the current literature on this topic.

Results

and conclusion Surgical removal of endometriosis can have a positive impact on the prognosis for spontaneous conception. Endometriosis should no longer be automatically surgically treated prior to in vitro fertilization (IVF) treatment or intracytoplasmic sperm injection (ICSI). Although there is no proven impact of ovarian endometriosis, deep infiltrating endometriosis and colorectal endometriosis on the probability of pregnancy after IVF or ICSI treatment, these lesions can potentially have a harmful effect during pregnancy. Similar content being viewed by others Literatur Al-Fadhli R, Kelly SM, Tulandi T, Tanr SL (2006) Effects of different stages of endometriosis on the outcome of in vitro fertilization. J Obstet Gynaecol Can 28(10):888–891 Ballester M, d’Argent EM, Morcel K, Belaisch-Allart J, Nisolle M, Daraï E (2012) Cumulative pregnancy rate after ICSI-IVF in patients with colorectal endometriosis: results of a multicentre study. Hum Reprod 27(4):1043–1049 Biacchiardi CP, Piane LD, Camanni M, Deltetto F, Delpiano EM, Marchino GL, Gennarelli G, Revelli A (2011) Laparoscopic stripping of endometriomas negatively affects ovarian follicular reserve even if performed by experienced surgeons. Reprod Biomed Online 23(6):740–746 Benaglia L, Pasin R, Somigliana E, Vercellini P, Ragni G, Fedele L (2011) Unoperated ovarian endometriomas and responsiveness to hyperstimulation. Hum Reprod 26(6):1356–1361 Benaglia L, Somigliana E, Santi G, Scarduelli C, Ragni G, Fedele L (2011) IVF and endometriosis-related symptom progression: insights from a prospective study. Hum Reprod 26(9):2368–2372 Benaglia L, Bermejo A, Somigliana E, Scarduelli C, Ragni G, Fedele L, Garcia-Velasco J (2012) Pregnancy outcome in women with endometriomas achieving pregnancy through IVF. 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Küpker, Baden-Baden Rights and permissions About this article Cite this article Shebl, O., Ebner, T. & Oppelt, P. Kinderwunsch und Schwangerschaft bei Endometriose. Gynäkologische Endokrinologie 14, 21–25 (2016). https://doi.org/10.1007/s10304-015-0052-0 Published: Issue date: DOI: https://doi.org/10.1007/s10304-015-0052-0 Schlüsselwörter - Operative Verfahren - Fertilität - In-vitro-Fertilisation - Intrazytoplasmatische Spermieninjektion - Adenomyose

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