Effect of delaying post-operative conception after conservative surgery for endometriosis

Edgardo Somigliana, Paolo Vercellini, Daguati R, Raffaella Daguati, Erika Giambattista, Giambattista E, Laura Benaglia, Luigi Fedele
Reproductive BioMedicine Online · 2009 · vol. 20(3) , pp. 410–415 · doi:10.1016/j.rbmo.2009.12.010 · PMID:20097135 · W2139419797
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This study investigated the impact of delaying conception after conservative surgery for endometriosis on reproductive outcomes.

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Abstract

The objective of this study was to determine whether delaying attempts to conceive after surgery for endometriosis impacts on reproductive prognosis. Patients operated on for endometriosis who were not seeking pregnancy at the time of surgery were selected (n=124) from a large survey regarding reproductive outcome of women with the disease. Pregnancy rate and rate of second surgery were compared between women who attempted conception within 12 months after surgery (n=61) and those compared who postponed attempts for 12 months or more (n=63). In women delaying attempted conception, the adjusted incidence rate ratio for pregnancy and repetitive surgery was 0.79 (95% CI 0.46-1.35) and 1.70 (95% CI 0.86-3.38), respectively. In conclusion, attempting conception shortly after surgery appears advisable since delaying is associated with a lower pregnancy rate and a higher rate of recurrence. However, these differences did not reach statistical significance and this advice is thus not mandatory. Larger studies are warranted to validate these conclusions.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fertilization Pregnancy Rate Adult Endometriosis Female Humans Postoperative Period Pregnancy Reoperation Secondary Prevention Time Factors

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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