Link between Endometriosis, Atherosclerotic Cardiovascular Disease, and the Health of Women Midlife

Taskin O, Omur Taskin, Ömür Taşkın, Rikhraj K, Kiran Rikhraj, Tan J, Justin Tan, Sedlak T, Tara Sedlak, Timothy Rowe, Rowe TC, Timothy C Rowe, Mohamed A. Bedaiwy
Journal of Minimally Invasive Gynecology · 2019 · vol. 26(5) , pp. 781–784 · doi:10.1016/j.jmig.2019.02.022 · PMID:31028947 · W2942151432
article OA: closed CC0 ⤵ 20 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated the association between endometriosis and atherosclerotic cardiovascular disease in midlife women.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Endometriosis and atherosclerotic cardiovascular disease (ASCVD) are both essentially diseases of inflammation. It is well established that inflammation is the leading mechanism in the initiation and maintenance of vascular injury and in the development and progression of atherosclerosis. Thus, if women with endometriosis do indeed have increased general inflammation, they are at increased risk of developing microvascular dysfunction and atherosclerosis. Currently available evidence suggests that young female patients with proven endometriosis may be at a higher lifetime risk of developing cardiovascular disease; this may be unrecognized due to the relatively young age of women found to have endometriosis. Other mechanisms proposed to explain the link between endometriosis and ASCVD include similarities in the genetic underpinnings of each condition, including microRNA dysfunction and the association between endometriosis and early menopause, a risk for developing ASCVD. Although physicians today primarily focus on traditional risk factors when evaluating an individual female patient's risk of developing ASCVD, we believe that a history of endometriosis should be included as a possible risk factor and needs further exploration. A better understanding of the mechanisms linking endometriosis with ASCVD will hopefully guide the implementation of new therapies to mitigate the increased cardiovascular disease burden that patients with endometriosis might face.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Atherosclerosis Cardiovascular Diseases Endometriosis Women's Health Adult Atherosclerosis Cardiovascular Diseases Comorbidity Endometriosis Female Hormone Replacement Therapy Humans Inflammation Menopause Middle Aged Ovary Ovary Risk Factors

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (32)

Cited by (21)

Source provenance

europepmc
last seen: 2026-08-09T06:10:49.860119+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:22:48.502547+00:00
License: CC0 · commercial use OK