The effect of peritoneal fluid from patients with endometriosis on murine sperm-oocyte interaction
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⤵ 42 in-corpus citations
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This study investigated how peritoneal fluid from endometriosis patients impacts sperm-oocyte binding and fertilization in a murine model.
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Abstract
It has been demonstrated that PF contains some factor or factors that interfere with effective gamete interaction as determined by an in vitro animal assay. PF from patients with mild endometriosis has an increased activity of this substance and/or additional inhibitory factors. In endometriosis, this peritoneal fluid factor or factors appear to be filterable and to a significant degree heat-labile. This observation may be of importance in explaining subfertility associated with early stages of endometriosis.
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References (5)
- Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay via openalex
- Sperm phagocytosis by human peritoneal macrophages: a possible cause of infertility in endometriosis via openalex
- W1999806406 via openalex
- W2398575063 via openalex
- W2409510670 via openalex
Cited by (42)
- Endometriosis affects the number of retrieved oocytes but not early embryonic development and live birth: a retrospective analysis of 716 IVF cycles 2023
- Iron overload in endometriosis peritoneal fluid induces early embryo ferroptosis mediated by HMOX1 2021
- Ultralong administration of gonadotropin-releasing hormone agonists before in vitro fertilization improves fertilization rate but not clinical pregnancy rate in women with mild endometriosis: a prospective, randomized, controlled trial 2020
- Effect of Endometriosis on IVF Outcomes in Cases of Single Embryo Transfer for first IVF Attempt in Patients under 35 2016
- Pathophysiology of Infertility in Endometriosis 2011
- Direct effect of macrophage migration inhibitory factor on sperm function: possible involvement in endometriosis-associated infertility 2007
- Elevated levels of macrophage migration inhibitory factor in the peripheral blood of women with endometriosis 2005
- How Does Endometriosis Cause Infertility? 2003
- Immunology and endometriosis 2003
- Effect of peritoneal fluid from women with endometriosis on implantation in the mouse model 2000
- Peritoneal fluid modulates the sperm acrosomal exocytosis induced by N-acetylglucosaminyl neoglycoprotein 1999
- Immunology of endometriosis 1999
- Pathophysiology of endometriosis-associated infertility 1999
- Is adenomyosis an immune disease? 1998
- Outcome of IVF in patients with endometriosis in comparison with tubal-factor infertility 1998
- Endometriosis-associated infertility 1997
- Pathophysiology. The biologic principles of disease 1997
- Basic research in endometriosis 1997
- Review of Peritoneal Factors that Affect Fertility in Patients With Mild Endometriosis 1996
- In vitro sperm phagocytosis by human peritoneal macrophages in endometriosis-associated infertility 1996
- The effect of peritoneal fluid from patients with endometriosis on human sperm function in vitro 1996
- The peritoneal environment in endometriosis 1996
- The effect of serum from infertile women with endometriosis on fertilization and early embryonic development in a murine in vitro fertilization model 1995
- Pathogenesis of Infertility in Endometriosis 1995
- Aberrant integrin expression in the endometrium of women with endometriosis 1994
- Endometriosis: Immune Cells and Their Products 1994
- An elicited intraperitoneal inflammatory response has no effect on the establishment of pregnancy in the mouse 1994
- Adverse effects on sperm movement characteristics in women with minimal and mild endometriosis 1993
- Inflammatory reaction in endometriotic tissue: an immunohistochemical study 1993
- Endometriosis-associated infertility 1993
- Pretreatment with gonadotrophin releasing hormone (GnRH) analogue prior to in vitro fertilisation for patients with endometriosis 1993
- The effect of preovulatory peritoneal fluid from cases of endometriosis on murine in vitro fertilization, embryo development, oviduct transport, and implantation 1992
- Comparison of cytokine levels and embryo toxicity in peritoneal fluid in infertile women with untreated or treated endometriosis 1992
- The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro 1992
- Pathogenesis of endometriosis 1992
- The peritoneal environment in endometriosis 1991
- Role of peritoneal inflammation in endometriosis-associated infertility 1991
- The stimulus responsible for the peritoneal fluid inflammation observed in infertile women with endometriosis 1991
- Immunomodulation in the treatment of endometriosis-associated subfertility: use of pentoxifylline to reverse the inhibition of fertilization by surgically induced endometriosis in a rodent model 1991
- Heterologous transplantation of activated murine peritoneal macrophages inhibits gamete interaction in vivo: a paradigm for endometriosis-associated subfertility 1990
- The effect of tumor necrosis factor on human sperm motility in vitro 1989
- Endometriosis as a cause of infertility 1989
Source provenance
- europepmc
- last seen: 2026-10-13T06:10:10.580696+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:37:52.028857+00:00
- unpaywall
- last seen: 2026-09-17T06:32:46.214484+00:00
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