Ultralong administration of gonadotropin-releasing hormone agonists before in vitro fertilization improves fertilization rate but not clinical pregnancy rate in women with mild endometriosis: a prospective, randomized, controlled trial

Apostolos Kaponis, Grigoris Chatzopoulos, Minas Paschopoulos, Ioannis Georgiou, Vaggelis Paraskevaidis, Konstantinos Zikopoulos, Konstantinos Tsiveriotis, Fuminori Taniguchi, Georgios Adonakis, George Adonakis, Tasuku Harada
Fertility and sterility · 2020 · vol. 113(4) , pp. 828–835 · doi:10.1016/j.fertnstert.2019.12.018 · PMID:32147182 · W3009213308
article OA: closed CC0 ⤵ 35 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

Pre-IVF administration of GnRH agonists for an ultralong duration improved fertilization rates in women with mild endometriosis but did not increase clinical pregnancy rates.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fertilization in Vitro Fertilization in Vitro Gonadotropin-Releasing Hormone Leuprolide Pregnancy Rate Adult Delayed-Action Preparations Delayed-Action Preparations Drug Administration Schedule Endometriosis Endometriosis Female Fertility Agents, Female Fertility Agents, Female Fertilization in Vitro Gonadotropin-Releasing Hormone Humans Leuprolide Pregnancy

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Cited by (35)

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europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
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pubmed
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License: CC0 · commercial use OK