Gonadotropin-Releasing Hormone Agonists for Endometriosis

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A 36-year-old woman with pelvic pain unresponsive to other treatments was prescribed a gonadotropin-releasing hormone agonist, which profoundly suppresses sex-steroid production but carries risks of bone density loss and memory impairment.

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Abstract

A 36-year-old woman with a presumptive diagnosis of endometriosis presents with long-standing pelvic pain that is not relieved by means of oral contraceptives or medroxyprogesterone. Treatment with a gonadotropin-releasing hormone agonist is recommended. Gonadotropin-releasing hormone agonists profoundly suppress gonadotropin secretion and sex-steroid production. Side effects include loss of bone mineral density and memory impairment.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Gonadotropin-Releasing Hormone Adult Bone Density Bone Density Endometriosis Endometriosis Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Pain Pain Practice Guidelines as Topic

Citation neighborhood

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References (34)

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