Endometriosis: Current and Emerging Therapies

In: Clinical Medicine Reviews in Women's Health · 2011 · vol. 3 , pp. 23–30 · doi:10.4137/cmrwh.s3269 · W1966866942
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-19 ⓘ

This review discusses current medical and surgical treatments for endometriosis, which involves endometrial tissue growing outside the uterus, and highlights emerging therapies and diagnostic potential from basic science research.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-26 · read from full text ⓘ

This review article synthesizes current and emerging therapeutic strategies for endometriosis, focusing on hormonal suppression and surgical interventions. It evaluates the efficacy of various medical treatments, including oral contraceptives, progestins, and gonadotropin-releasing hormone agonists, while also addressing the role of laparoscopic excision in managing pain and improving fertility outcomes. The authors note that treatment selection often depends on patient symptoms, desire for pregnancy, and previous response to therapy, highlighting the lack of a single curative option. This paper is centrally about endometriosis — specifically reviewing pharmacological and surgical management options for the disease.

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Abstract

Endometriosis remains a cause of significant morbidity in reproductive-aged women resulting in pelvic pain, pelvic masses and infertility. Endometriosis is defined as the presence of endometrial glands and stroma outside of their normal intrauterine location, most commonly in the dependent portions of the pelvis. Endometriosis can be treated with medical therapies or surgery, both conservative and radical. The medical therapies include oral contraceptive pills, progestins, gonadotropin releasing hormone analogues and danazol. All of these medical therapies induce a hormonal steady state that results in an environment not conducive to the growth of endometriosis. Surgical therapies for endometriosis-associated pain include conservative treatments which include removal of endometriotic implants and adhesions with restoration of normal anatomy. Radical surgery involves removal of the uterus with or without removal of the ovaries in patients who have completed childbearing. Basic science discoveries about endometriosis hold the promise for less invasive diagnostic tests and improved therapies.
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Condition tags

endometriosisinfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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