Tumor markers and transvaginal ultrasonography in the diagnosis of endometrioma
article
OA: closed
CC0
⤵ 39 in-corpus citations
AI-generated summary
Transvaginal ultrasonography alone showed strong agreement with surgical findings in diagnosing endometrioma, outperforming combined tumor marker tests.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
OBJECTIVE: To evaluate the accuracy of CA 19.9 plasma levels (with or without CA 125 levels) combined with transvaginal ultrasonography in the differential diagnosis of endometrioma. METHODS: One hundred eighteen consecutive premenopausal nonpregnant women had laparoscopy or laparotomy between November 1994 and November 1995 because of the presence of a persistent adnexal mass. They underwent transvaginal ultrasonography and measurement of CA 19.9 and CA 125 plasma levels within 2 days before surgery. The ultrasonographic impression and the tumor marker values were compared with the histopathologic diagnosis. The overall agreement between the test result and the actual outcome was calculated using the kappa statistic. RESULTS: Transvaginal ultrasonography had a strong agreement between test result and surgery (kappa value 0.84), whereas the combined methods were associated with a lower kappa value (range 0.24-0.80). CONCLUSION: Transvaginal ultrasonography used alone is the most cost-effective method in the preoperative differential diagnosis of endometrioma.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (22)
- Abnormally High Values of CA 125 and CA 19-9 in Women with Benign Tumors via openalex
- Diagnostic and operative gynecologic laparoscopy via openalex
- Laparoscopic ovarian puncture for correct staging of endometriosis via openalex
- Serum levels of the oncofetal antigens CA-125, CA 19-9 and CA 15-3 in patients with endometriosis via openalex
- The role of color Doppler in diagnosis of endometriomas via openalex
- Treatment of nonendometriotic benign adnexal cysts: A randomized comparison of laparoscopy and laparotomy via openalex
- W2030146379 via openalex
- W2051639596 via openalex
- W2065206330 via openalex
- W2082217892 via openalex
- W2131978815 via openalex
- W2150290224 via openalex
- W2413678815 via openalex
- W2414735600 via openalex
- W2417052106 via openalex
- W10868991 via openalex
- W2477008945 via openalex
- W91969275 via openalex
- W1509565492 via openalex
- W1966367305 via openalex
- W1970789379 via openalex
- W2021499511 via openalex
Cited by (38)
- Evaluation of Ki-67 staining index and BRAF mutation in women diagnosed with advanced endometriosis 2023
- Serum antimüllerian hormone concentration increases with ovarian endometrioma size 2019
- Models Including Serum CA-125, BMI, Cyst Pathology, Dysmenorrhea or Dyspareunia for Diagnosis of Endometriosis 2018
- Biomarkers in Endometriosis 2018
- Combination of the non-invasive tests for the diagnosis of endometriosis 2016
- Diagnóstico de la Endometriosis 2016
- Imaging modalities for the non-invasive diagnosis of endometriosis 2016
- Blood biomarkers for the non-invasive diagnosis of endometriosis 2016
- The Ovarian Endometrioma: Clinical Setting and Ultrasound Findings 2013
- Endometrioma: Computed Tomography and Magnetic Resonance Imaging 2013
- The prediction of pouch of Douglas obliteration using offline analysis of the transvaginal ultrasound 'sliding sign' technique: inter- and intra-observer reproducibility 2013
- Ultrasound-guided aspiration and ethanol sclerotherapy for treating endometrial cysts 2010
- Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses 2009
- Color Doppler Ultrasound Indices in Endometriotic Cysts 2009
- Ultrasonographic Assessment of Ovarian Endometrioma 2008
- Imagerie de l'endométriose 2007
- Accuracy of transvaginal sonography and rectal endoscopic sonography in the diagnosis of deep infiltrating endometriosis 2007
- Imaging in endometriosis 2007
- Pathologie organique de l'ovaire 2006
- Acoustic Streaming in Ovarian Cysts 2005
- La diagnosi di endometriosi 2005
- Laser surgery for endometriosis 2005
- Laser surgery for endometriosis 2005
- Removal of endometriomas before in vitro fertilization does not improve fertility outcomes: a matched, case–control study 2004
- Epidemiology of Endometriosis 2003
- Imaging in endometriosis 2003
- Endometriosis is a Surgical Disease 2003
- Acoustic streaming: a new technique for assessing adnexal cysts 2003
- Staging of Pelvic Endometriosis: Role of Sonographic Appearance in Determining Extension of Disease and Modulating Surgical Approach 2003
- A systematic review of the accuracy of ultrasound in the diagnosis of endometriosis 2002
- Endometriosis: Radiologic-Pathologic Correlation 2001
- Performance of US in the Diagnosis of Endometrioma 2000
- Role of color Doppler ultrasonography in the diagnosis of endometriotic cyst. 2000
- Immunohistochemical analysis of CA125, CA19–9, and Ki-67 in stage III or IV endometriosis: positive correlation between serum CA125 level and endometriotic epithelial cell proliferation 2000
- Endometriomas: Diagnostic Performance of US 1999
- The diagnosis of endometriomas using colour Doppler energy imaging 1998
- Biases in the endometriosis literature 1998
- The preoperative evaluation of ovarian tumors can be improved? 1997
Source provenance
- europepmc
- last seen: 2026-09-27T09:11:36.575535+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:57.821266+00:00
- unpaywall
- last seen: 2026-10-03T06:31:36.481334+00:00
License: CC0
· commercial use OK