Anna Maria Paoletti

INTRODUCTION: Endometriosis is a chronic disease characterized by endometriotic cells implanted outside the uterus triggering a chronic inflammatory state. Estradiol stimulates the endometriotic implants, which overexpress estrogen receptor…

Surgery for benign gynecologic conditions may lead to infertility complications. In a cross-sectional study we investigated depressive and anxiety symptoms, Quality of Life (QoL), and coping strategies in women with benign gynecologic condi…

Uterine fibroids (UFs) are the most common gynaecological benign disease. Even though often asymptomatic, UFs can worsen women's health and their quality of life, causing heavy bleeding and anaemia, pelvic discomfort and reduced fertility. …

PURPOSE: The aim of the present study was to evaluate the effectiveness of the ultramicronized-palmitoylethanolamide (um-PEA) and co-micronised palmitoylethanolamide/polydatin m(PEA/PLD) in the management of chronic pelvic pain related to e…

Endometriosis is a chronic multifactorial disease. It is caused by the spread of endometrial glands and stroma outside the uterine cavity. The transvaginal ultrasound is considered the first-line, noninvasive diagnostic method for the accur…

Pelvic inflammatory disease (PID) is a pathology of a woman's reproductive organs that originates from an infectious process spread through the cervix to the uterus, fallopian tubes up to the ovaries, and pelvic peritoneum. PID is the main …

This observational study was conducted in premenopausal women who presented themselves at the Obstetrics and Gynecology Department of the University Hospital of Cagliari (Italy), for heavy menstrual bleeding (HMB) dependent on uterine myoma…

OBJECTIVES: The aim of this study was to evaluate the use of ultrasound (US) soft markers as a first-line imaging tool to raise suspicion of rectosigmoid (RS) involvement in women suspected of having deep endometriosis. METHODS: We included…

INTRODUCTION: Suppression of sex-steroid secretion is required in a variety of gynecological conditions. This can be achieved using gonadotropin releasing hormone (GnRH) agonists that bind pituitary gonadotropin receptors and antagonize the…

In the menopausal transition (MT), combined oral contraceptive (COC) should be chosen accordingly to its neutrality on liver metabolism and to its ability to counter the increase of fat mass (FM) that occurs in this reproductive period of l…

Deep pelvic endometriosis is defined as subperitoneal infiltration of endometrial implants in the uterosacral ligaments, rectum, rectovaginal septum, vagina, or bladder. Although laparoscopy and biopsy remain the gold standard for diagnosis…

The COCs evolution has been obtained with new and differents progestinic compounds associated with lower doses of EE (ethinylestradiol). The revolution in the COCs field is the introduction of estradiol valerate (E2V), ester of the natural …

OBJECTIVES: The purpose of this study was to assess whether a single determination of the serum cancer antigen 125 (CA-125) level provides additional information to sonography for specific diagnosis of benign adnexal masses in premenopausal…

To evaluate 1. the prevalence of ultrasonographic diagnosis of deep endometriosis in patients with clinical suspicion and 2. to assess mean gray value (MGV) of nodules of deep endometriosis in different location also evaluating the reproduc…

To compare two different methods (manual sampling of all the cyst and semiautomated spherical sampling from the central part of cyst) for performing mean gray value (MGV) evaluation of cystic content in endometriomas using Virtual Organ Com…

To standardize the image display for the assessment deep pelvic endometriosis using three dimensional ultrasonography (3DTVS). Twenty volumes from women with surgically confirmed of deep infiltrating endometriosis (DIE) at level of rectovag…

Abstract Deep pelvic endometriosis is defined as subperitoneal infiltration of endometrial implants in the uterosacral ligaments, rectum, rectovaginal septum, vagina, or bladder. Although laparoscopy and biopsy remain the gold standard for …

Ovarian cysts are a common cause of hospital admission in several countries. For this reason, and because of the increasing impact of minimal access surgery in clinical practice, a preoperative assessment that offers a reasonable degree of …

ObjectiveTo verify if a 6-month period of hypoestrogenism due to chronic treatment with GnRH analogue (GnRH-a) causes irreversible bone loss in young women.DesignControlled clinical study in volunteer women.SettingDepartment of Obstetrics a…

OBJECTIVE: To verify if a 6-month period of hypoestrogenism due to chronic treatment with GnRH analogue (GnRH-a) causes irreversible bone loss in young women. DESIGN: Controlled clinical study in volunteer women. SETTING: Department of Obst…

OBJECTIVE: To evaluate the accuracy of CA 19.9 plasma levels (with or without CA 125 levels) combined with transvaginal ultrasonography in the differential diagnosis of endometrioma. METHODS: One hundred eighteen consecutive premenopausal n…