Pregnancy outcome in women with endometriomas achieving pregnancy through IVF

Laura Benaglia, Alfonso Bermejo, Bermejo A, Edgardo Somigliana, Scarduelli C, Claudia Scarduelli, C. Scarduelli, Guido Ragni, Ragni G, G. Ragni, Luigi Fedele, Juan A Garcia-Velasco, Juan A. García-Velasco
Human Reproduction · 2012 · vol. 27(6) , pp. 1663–1667 · doi:10.1093/humrep/des054 · PMID:22447627 · W2136834021
Observational OA: bronze CC0 ⤵ 75 in-corpus citations
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This study investigated whether the presence of ovarian endometriomas in women undergoing IVF negatively impacts pregnancy outcomes.

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Abstract

BACKGROUND: There is a growing consensus that ovarian endometriomas should not be systematically removed in women selected for IVF. However, some recent evidence suggested that the presence of these cysts may negatively affect the course of pregnancy. METHODS: We set up a multicenter retrospective cohort study, including two infertility units. We analyzed data from patients achieving singleton clinical pregnancies through IVF comparing the pregnancy outcome between 78 pregnant women with endometriomas at the time of IVF and 156 patients who achieved pregnancy through IVF without endometriomas. RESULTS: The number of live births in women with and without endometriomas were 61 (78%) and 130 (83%), respectively (P = 0.39). The adjusted odds ratio (OR) of live birth in affected cases was 0.79 [95% confidence interval (CI): 0.38-1.68]. No differences were observed in late pregnancy and neonatal outcomes between the two groups. In particular, the rate of preterm birth and small-for-gestational age (SGA) was similar. The adjusted ORs were 0.47 (95% CI: 0.14-1.54) and 0.56 (95% CI: 0.12-2.56), respectively. CONCLUSIONS: Women with endometriomas achieving pregnancy through IVF do not seem to be exposed to a significant increased risk of obstetrical complications.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fertilization in Vitro Fertilization in Vitro Infertility, Female Pregnancy Outcome Pregnancy Outcome Adult Adult Cohort Studies Cohort Studies Endometriosis Endometriosis Female Female Humans Humans Infant, Newborn Infant, Newborn Infant, Small for Gestational Age Infant, Small for Gestational Age

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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Cited by (50)

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