Oxidative Stress and the Pathogenesis of Endometriosis

Sajal Gupta; Anjali Chandra; Shubhangi Kesavan; Deborah Eapen

doi:10.5005/jp/books/11032_5

Oxidative Stress and the Pathogenesis of Endometriosis

Sajal Gupta, Anjali Chandra, Shubhangi Kesavan, Deborah Eapen

In: Endometriosis: Current Management and Future Trends · 2010 · pp. 31 · doi:10.5005/jp/books/11032_5 · W2965727015

book-chapter OA: closed CC0 ⤵ 3 in-corpus citations

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This paper reviews the role of oxidative stress in the development and progression of endometriosis, highlighting its contribution to inflammation, pain, and infertility associated with the condition.

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endometriosis

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References (79)

Aberrant Expression of Leptin in Human Endometriotic Stromal Cells Is Induced by Elevated Levels of Hypoxia Inducible Factor-1α via openalex
Ablation of Leptin Signaling Disrupts the Establishment, Development, and Maintenance of Endometriosis-Like Lesions in a Murine Model via openalex
Cell of the mucous membrane of the female genital tract in culture: A comparative study with regard to the histogenesis of endometriosis via openalex
Comparison of cytokine levels and embryo toxicity in peritoneal fluid in infertile women with untreated or treated endometriosis via openalex
Correction to “Eisermann J, Gast MJ, Pineda J, Odem RR, Collins JL: Tumor necrosis factor in peritoneal fluid of women undergoing laparoscopic surgery. Fertil Steril 50:573, 1988” via openalex
De novo formation of adhesions in endometriosis: the role of iron and free radical reactions via openalex
Dysregulation of interleukin-6 responses in ectopic endometrial stromal cells: correlation with decreased soluble receptor levels in peritoneal fluid of women with endometriosis. via openalex
Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis via openalex
Effects of oxidants and antioxidants on proliferation of endometrial stromal cells via openalex
Endometriosis: A Disease of Oxidative Stress? via openalex
Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons via openalex
Enhancement of Human Monocyte and Peritoneal Macrophage Chemiluminescence Activities in Women With Endometriosis via openalex
Female Infertility and Free Radicals: Potential Role in Adhesions and Endometriosis via openalex
Immunobiology of endometriosis via openalex
Impact of ovarian endometrioma on assisted reproduction outcomes via openalex
Importance portance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility via openalex
Increased Leptin Levels in Serum and Peritoneal Fluid of Patients with Pelvic Endometriosis1 via openalex
Increased levels of interleukin-6 and interleukin-10 in the peritoneal fluid of patients with endometriosis via openalex
Infliximab may reverse the toxic effects induced by tumor necrosis factor alpha in human spermatozoa: an in vitro model via openalex
Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis) via openalex
Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model via openalex
Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid via openalex
Laparoscopic surgery in endometriosis. via openalex
Leptin is not involved in the pathophysiology of endometriosis-related infertility via openalex
[Lipid peroxides, tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) in peritoneal fluid from infertile women with minimal and mild endometriosis]. via openalex
Oxidative stress and peritoneal endometriosis via openalex
Oxidative stress may be a piece in the endometriosis puzzle via openalex
Pathogenesis of Endometriosis via openalex
Peritoneal fluid cytokines and the relationship with endometriosis and pain via openalex
Peritoneal fluid leptin is associated with chronic pelvic pain but not infertility in endometriosis patients* via openalex
Peritoneal Fluid lnterleukin‐1β and Tumor Necrosis Factor in Patients With Benign Gynecologic Disease via openalex
Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trial via openalex
Proteome analysis of human mesothelial cells during epithelial to mesenchymal transitions induced by shed menstrual effluent via openalex
Retrograde menstruation in healthy women and in patients with endometriosis. via openalex
Role of oxidative stress in endometriosis via openalex
Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markers. via openalex
Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease via openalex
The elusive diagnostic test for endometriosis via openalex
The peritoneal fluid concentration of leptin is increased in women with peritoneal but not ovarian endometriosis via openalex
The tumor necrosis factor-α promoter −1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population via openalex
Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis via openalex
Transcriptional Characterizations of Differences between Eutopic and Ectopic Endometrium via openalex
W2100503022 via openalex
W2106029185 via openalex
W1992451410 via openalex
W2108323104 via openalex
W2113369935 via openalex
W2115993724 via openalex
W2117673388 via openalex
W1985013537 via openalex
W2126253259 via openalex
W2126426760 via openalex
W2129757265 via openalex
W1850638409 via openalex
W1602283349 via openalex
W2148700883 via openalex
W2157942810 via openalex
W1590709474 via openalex
W2278570238 via openalex
W2342750321 via openalex
W2400464731 via openalex
W1522051702 via openalex
W1500275233 via openalex
W2418200982 via openalex
W2039639759 via openalex
W192577498 via openalex
W2038339768 via openalex
W2042642675 via openalex
W2043842027 via openalex
W2037263323 via openalex
W2057085814 via openalex
W2057098127 via openalex
W2057684012 via openalex
W2067526555 via openalex
W2016958610 via openalex
W2016845562 via openalex
W2071453856 via openalex
W2010793153 via openalex
W2100352028 via openalex

Cited by (3)

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License: CC0 · commercial use OK

[1] Aberrant Expression of Leptin in Human Endometriotic Stromal Cells Is Induced by Elevated Levels of Hypoxia Inducible Factor-1α via openalex

[2] Ablation of Leptin Signaling Disrupts the Establishment, Development, and Maintenance of Endometriosis-Like Lesions in a Murine Model via openalex

[3] Cell of the mucous membrane of the female genital tract in culture: A comparative study with regard to the histogenesis of endometriosis via openalex

[4] Comparison of cytokine levels and embryo toxicity in peritoneal fluid in infertile women with untreated or treated endometriosis via openalex

[5] Correction to “Eisermann J, Gast MJ, Pineda J, Odem RR, Collins JL: Tumor necrosis factor in peritoneal fluid of women undergoing laparoscopic surgery. Fertil Steril 50:573, 1988” via openalex

[6] De novo formation of adhesions in endometriosis: the role of iron and free radical reactions via openalex

[7] Dysregulation of interleukin-6 responses in ectopic endometrial stromal cells: correlation with decreased soluble receptor levels in peritoneal fluid of women with endometriosis. via openalex

[8] Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis via openalex

[9] Effects of oxidants and antioxidants on proliferation of endometrial stromal cells via openalex

[10] Endometriosis: A Disease of Oxidative Stress? via openalex

[11] Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons via openalex

[12] Enhancement of Human Monocyte and Peritoneal Macrophage Chemiluminescence Activities in Women With Endometriosis via openalex

[13] Female Infertility and Free Radicals: Potential Role in Adhesions and Endometriosis via openalex

[14] Immunobiology of endometriosis via openalex

[15] Impact of ovarian endometrioma on assisted reproduction outcomes via openalex

[16] Importance portance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility via openalex

[17] Increased Leptin Levels in Serum and Peritoneal Fluid of Patients with Pelvic Endometriosis1 via openalex

[18] Increased levels of interleukin-6 and interleukin-10 in the peritoneal fluid of patients with endometriosis via openalex

[19] Infliximab may reverse the toxic effects induced by tumor necrosis factor alpha in human spermatozoa: an in vitro model via openalex

[20] Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis) via openalex

[21] Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model via openalex

[22] Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid via openalex

[23] Laparoscopic surgery in endometriosis. via openalex

[24] Leptin is not involved in the pathophysiology of endometriosis-related infertility via openalex

[25] [Lipid peroxides, tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) in peritoneal fluid from infertile women with minimal and mild endometriosis]. via openalex

[26] Oxidative stress and peritoneal endometriosis via openalex

[27] Oxidative stress may be a piece in the endometriosis puzzle via openalex

[28] Pathogenesis of Endometriosis via openalex

[29] Peritoneal fluid cytokines and the relationship with endometriosis and pain via openalex

[30] Peritoneal fluid leptin is associated with chronic pelvic pain but not infertility in endometriosis patients* via openalex

[31] Peritoneal Fluid lnterleukin‐1β and Tumor Necrosis Factor in Patients With Benign Gynecologic Disease via openalex

[32] Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trial via openalex

[33] Proteome analysis of human mesothelial cells during epithelial to mesenchymal transitions induced by shed menstrual effluent via openalex

[34] Retrograde menstruation in healthy women and in patients with endometriosis. via openalex

[35] Role of oxidative stress in endometriosis via openalex

[36] Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markers. via openalex

[37] Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease via openalex

[38] The elusive diagnostic test for endometriosis via openalex

[39] The peritoneal fluid concentration of leptin is increased in women with peritoneal but not ovarian endometriosis via openalex

[40] The tumor necrosis factor-α promoter −1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population via openalex

[41] Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis via openalex

[42] Transcriptional Characterizations of Differences between Eutopic and Ectopic Endometrium via openalex

[43] W2100503022 via openalex

[44] W2106029185 via openalex

[45] W1992451410 via openalex

[46] W2108323104 via openalex

[47] W2113369935 via openalex

[48] W2115993724 via openalex

[49] W2117673388 via openalex

[50] W1985013537 via openalex

[51] W2126253259 via openalex

[52] W2126426760 via openalex

[53] W2129757265 via openalex

[54] W1850638409 via openalex

[55] W1602283349 via openalex

[56] W2148700883 via openalex

[57] W2157942810 via openalex

[58] W1590709474 via openalex

[59] W2278570238 via openalex

[60] W2342750321 via openalex

[61] W2400464731 via openalex

[62] W1522051702 via openalex

[63] W1500275233 via openalex

[64] W2418200982 via openalex

[65] W2039639759 via openalex

[66] W192577498 via openalex

[67] W2038339768 via openalex

[68] W2042642675 via openalex

[69] W2043842027 via openalex

[70] W2037263323 via openalex

[71] W2057085814 via openalex

[72] W2057098127 via openalex

[73] W2057684012 via openalex

[74] W2067526555 via openalex

[75] W2016958610 via openalex

[76] W2016845562 via openalex

[77] W2071453856 via openalex

[78] W2010793153 via openalex

[79] W2100352028 via openalex