Pituitary–ovarian function in women with minimal or mild endometriosis and otherwise unexplained infertility

Bancroft K, K. Bancroft, Charles A. Williams, Vaughan Williams Ca, C A Vaughan Williams, Elstein M, Max Elstein, M Elstein
Clinical endocrinology · 1992 · vol. 36(2) , pp. 177–181 · doi:10.1111/j.1365-2265.1992.tb00954.x · PMID:1568349 · W2117877508
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This study compared pituitary-ovarian function in women with minimal/mild endometriosis and infertility to fertile controls, finding dysfunction in 82% of study cycles.

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Abstract

OBJECTIVE: To determine whether abnormalities of pituitary-ovarian function are associated with minor degrees of endometriosis in women with otherwise unexplained infertility. DESIGN: Comparison of pituitary-ovarian function in a group of 22 patients with that in a control group of 10 healthy fertile women. PATIENTS: Twenty-two women with minimal or mild endometriosis and otherwise unexplained infertility. MEASUREMENTS: Ovarian ultrasound and radioimmunoassay of pituitary and ovarian hormones. RESULTS: Abnormalities, including luteinization of unruptured follicles, broad LH surges and low concentrations of progesterone during the luteal phase, were demonstrated in 82% of study cycles. CONCLUSION: Pituitary-ovarian dysfunction appears to be associated with minimal or mild endometriosis in women with otherwise unexplained infertility but the diversity of endocrine abnormalities demonstrated suggests that endometriosis is unlikely to be an aetiological factor in their development.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Ovarian Neoplasms Ovary Pituitary Gland Adolescent Adult Endometriosis Endometriosis Estradiol Estradiol Female Follicle Stimulating Hormone Follicle Stimulating Hormone Humans Infertility, Female Infertility, Female Luteinizing Hormone Luteinizing Hormone Menstrual Cycle

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (20)

Cited by (22)

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