The vitamin E-binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis

Seeber BE, Beata E Seeber, Beata Seeber, Czech T, Theresa Czech, Buchner H, Hannes Buchner, Kurt T. Barnhart, Barnhart KT, Christoph Seger, Guenter Daxenbichler, Daxenbichler G, Ludwig Wildt, L. Wildt, Wildt L, Hans Dieplinger, Dieplinger H
Fertility and sterility · 2010 · vol. 94(7) , pp. 2923–2926 · doi:10.1016/j.fertnstert.2010.05.008 · PMID:20858448 · PMC2996608 · W2063520912
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Afamin levels in peritoneal fluid were altered in women with endometriosis, correlating with vitamin E and indicating increased oxidative stress in the peritoneal cavity.

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The provided text consists solely of the acknowledgments and conflict of interest disclosures for a study titled "The vitamin E–binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis." It does not contain the abstract, methods, results, or discussion sections necessary to summarize the research findings, population, or limitations. Consequently, no scientific data regarding afamin levels or peritoneal fluid analysis can be extracted from this excerpt. Relevance to endometriosis: The paper's title explicitly identifies it as a study concerning endometriosis, specifically investigating biomarkers in peritoneal fluid, although the full content required for summary is missing.

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Abstract

The objective of this case-control study of 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis and to test afamin as a diagnostic marker of endometriosis. Afamin levels were altered significantly in the peritoneal fluid of women with endometriosis compared with disease-free controls, correlated with vitamin E levels, and are consistent with increased oxidative stress in the peritoneal cavity of women with endometriosis.
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Ack

The authors are grateful to Ms. Linda Fineder, Ms. Andrea Sapinsky, and Ms. Ruth Lenners for excellent technical assistance and to Stephan Kropshofer, M.D., and Sigfried Fessler, M.D., for help in specimen collection.

Fn Group

K.T.B. is a consultant for Pfizer and Swiss Precision Diagnostics and a clinical trial investigator for Boehringer Ingelheim, Third Wave, Wyeth-Ayerst, and Xanodyne. H.D. is owner of Vitater Biotechnology. B.E.S. has nothing to disclose. T.C. has nothing to disclose. H.B. has nothing to disclose. C.S. has nothing to disclose. G.D. has nothing to disclose. L.W. has nothing to disclose. Supported by grants from the Jubiläumsfonds of the Austrian National Bank to B.E.S. (Project 12724) and H.D. (12529) and from the Austrian Science Fund to H.D. (P19969-B11).

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Condition tags

endometriosisadenomyosisinfertility

MeSH descriptors

Ascitic Fluid Carrier Proteins Endometriosis Glycoproteins Peritoneal Diseases Serum Albumin Adolescent Adolescent Adult Adult Ascitic Fluid Ascitic Fluid Ascitic Fluid Ascitic Fluid Carrier Proteins Carrier Proteins Carrier Proteins Carrier Proteins Case-Control Studies Case-Control Studies

Citation neighborhood (2-hop)

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