Total antioxidant status of peritoneal fluid in infertile women

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This study measured the total antioxidant status of peritoneal fluid in infertile women to assess its potential role in infertility.

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Abstract

ObjectiveTo determine whether impairment of the antioxidant systems of peritoneal fluid might be a factor responsible for infertility.Study designTotal antioxidant status was measured in peritoneal fluid obtained from 18 infertile women suffering from minimal or mild endometriosis, 23 patients with unexplained infertility, 12 women with tubal infertility and 13 fertile women.ResultsTotal antioxidant status was significantly lower in peritoneal fluid from women with unexplained infertility (0.49+/-0.21 mmol/l) compared to both fertile patients (0.67+/-0.24 mmol/l, P=0.02) and women with tubal infertility (0.76+/-0.26 mmol/l, P=0.001). Peritoneal fluid total antioxidant status did not differ significantly between patients with endometriosis (0.61+/-0.2 mmol/l), tubal infertility and the fertile group (P>0.05).ConclusionsOur results suggest that low antioxidant status in peritoneal fluid may play a role in the pathogenesis of infertility.

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Condition tags

endometriosis

MeSH descriptors

Antioxidants Ascitic Fluid Infertility, Female Antioxidants Ascitic Fluid Endometriosis Endometriosis Endometriosis Fallopian Tube Diseases Fallopian Tube Diseases Fallopian Tube Diseases Female Humans Infertility, Female Infertility, Female

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