The role of iron metabolism and oxidative stress in the pathogenesis of endometriosis

Polak G; Grzegorz Polak; Iwona Wertel; Wojciech Kwaśniewski; Derewianka-Polak M; Jan Kotarski; Magdalena Derewianka-Polak; Kotarski J

doi:10.17772/gp/1542

The role of iron metabolism and oxidative stress in the pathogenesis of endometriosis

Polak G, Grzegorz Polak, Iwona Wertel, Wojciech Kwaśniewski, Derewianka-Polak M, Jan Kotarski, Magdalena Derewianka-Polak, Kotarski J

Ginekologia polska · 2013 · vol. 84(1) , pp. 62–4 · doi:10.17772/gp/1542 · PMID:23488312 · W2331614816

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Disrupted iron metabolism is implicated in causing oxidative stress within the peritoneal cavity, contributing to the pathogenesis of endometriosis.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-19 · read from full text ⓘ

The provided text contains a collection of unrelated medical snippets covering topics such as follicle-stimulating hormone interpretation, emotional deprivation, procalcitonin markers, liver function, abdominal pain, lubricant selection, lung cancer, amniocentesis, and body composition. None of these excerpts discuss iron metabolism or oxidative stress, nor do they address the pathogenesis of endometriosis. The title "The role of iron metabolism and oxidative stress in the pathogenesis of endometriosis" does not appear to correspond to any of the visible content in the provided paper body. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Despite many years of extensive investigations and increasing number of studies, the pathogenesis of endometriosis remains unclear Accumulated data suggests that disrupted iron metabolism may induce oxidative stress in the peritoneal cavity of endometriosis patients.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Iron Oxidative Stress Endometriosis Female Humans Iron Oxidative Stress Peritoneal Cavity Peritoneal Cavity

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (3)

Source provenance

europepmc: last seen: 2026-09-21T06:08:07.822426+00:00
openalex: last seen: 2026-06-10T17:14:06.276822+00:00
pubmed: last seen: 2026-05-13T22:19:05.543671+00:00

License: CC0 · commercial use OK

[1] Contents of Endometriotic Cysts, Especially the High Concentration of Free Iron, Are a Possible Cause of Carcinogenesis in the Cysts through the Iron-Induced Persistent Oxidative Stress via openalex

[2] Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis via openalex

[3] Endometriosis: A Disease of Oxidative Stress? via openalex

[4] Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons via openalex

[5] Endothelial nitric oxide synthase in the endometrium during the menstrual cycle in patients with endometriosis and adenomyosis via openalex

[6] Evidence for Oxidatively Modified Lipid-Protein Complexes in Endometrium and Endometriosis via openalex

[7] Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model via openalex

[8] Levels of Antibodies to Transferrin and Alpha 2‐HS Glycoprotein in Women With and Without Endometriosis via openalex

[9] Levels of Transferrin and Alpha 2-HS Glycoprotein in Women with and without Endometriosis via openalex

[10] Lipid peroxidation and vitamin E in serum and follicular fluid of infertile women with peritoneal endometriosis submitted to controlled ovarian hyperstimulation: a pilot study via openalex

[11] Lipid peroxidation in the peritoneal fluid of infertile women with peritoneal endometriosis via openalex

[12] Oxidative stress may be a piece in the endometriosis puzzle via openalex

[13] Potential involvement of hemoglobin and heme in the pathogenesis of peritoneal endometriosis via openalex

[14] Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease via openalex

[15] The role of the oxidative-stress in the endometriosis-related infertility via openalex

[16] Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis via openalex

[17] Total antioxidant status of peritoneal fluid in infertile women via openalex

[18] W1681346990 via openalex