Enlarged uterus: differentiation between adenomyosis and leiomyoma with MR imaging
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MR imaging accurately differentiated adenomyosis from leiomyoma in enlarged uteri by identifying characteristic signal intensities and lesion margins, correlating well with surgical pathology.
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Abstract
The potential of magnetic resonance (MR) imaging in differentiation of adenomyosis from leiomyoma was evaluated in 93 patients who had a palpable enlarged uterus that was suspect for leiomyoma or adenomyosis. In all cases, MR images were correlated with surgical/pathologic findings. Pathologic findings showed that 71 enlarged uteri were due to leiomyoma, including one leiomyosarcoma, and 16 were due to adenomyosis. The other six patients were shown to have an enlarged uterus attributable to simultaneous involvement of both lesions. On T2-weighted images, adenomyosis appeared as an ill-defined, relatively homogeneous low-signal-intensity area embedded with sparse high-intensity spots. In contrast, leiomyomas were well-circumscribed masses with a spectrum of signal intensity. The cause of uterine enlargement was correctly diagnosed with MR images in 92 of the 93 cases. It is concluded that MR imaging is highly accurate in helping to distinguish between adenomyosis and leiomyoma in cases of enlarged uterus.
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Cited by (50)
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- Prevalence of Female Pelvic Pathologies: Cross-sectional Study among Patients Undergoing Magnetic Resonance Imaging for Pelvic Assessment 2021
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- Faculty Opinions recommendation of Pregnancy rate in women with adenomyosis undergoing fresh or frozen embryo transfer cycles following gonadotropin-releasing hormone agonist treatment. 2019
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- Phenotypic characterization of adenomyosis occurring at the inner and outer myometrium 2017
- The benefit of adenomyomectomy on fertility outcomes in women with rectovaginal endometriosis with coexisting adenomyosis 2016
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- Ultrasonography of Uterine Leiomyomas 2016
- Differences in clinical characteristics for the determination of adenomyosis coexisting with leiomyomas 2015
- Comparative analysis of changes in MR imaging of pre and post intrauterine progesterone implants in adenomyosis cases 2015
- Adenomyosis: A Clinical Review of a Challenging Gynecologic Condition 2015
- What are the most reliable signs for the radiologic diagnosis of uterine adenomyosis? An ultrasound and MRI prospective 2015
- Diagnóstico de la adenomiosis 2014
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- Decidualized adenomyosis during pregnancy and post delivery: three cases of magnetic resonance imaging findings 2013
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- Adenomyosis has no adverse effects on IVF/ICSI outcomes in women with endometriosis treated with long-term pituitary down-regulation before IVF/ICSI 2010
- Adenomyosis: still largely under-diagnosed 2009
- CT features of adenomyosis 2008
- Uterine artery embolisation for symptomatic adenomyosis--mid-term results 2008
- Adenomyosis and 'endometrial-subendometrial myometrium unit disruption disease' are two different entities 2008
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- Do anticholinergic agents suppress uterine peristalsis and sporadic myometrial contractions at cine MR imaging? 2007
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