Progesterone and progestational compounds attenuate tumor necrosis factor alpha–induced interleukin-8 production via nuclear factor kappaB inactivation in endometriotic stromal cells

Sayako Horie, Tasuku Harada, Masahiro Mitsunari, Fuminori Taniguchi, Tomio Iwabe, Naoki Terakawa
Fertility and sterility · 2005 · vol. 83(5) , pp. 1530–1535 · doi:10.1016/j.fertnstert.2004.11.042 · PMID:15866594 · W2035455398
article OA: bronze CC0 ⤵ 132 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Progesterone and progestational compounds were found to reduce TNFα-induced IL-8 production by inactivating NF-κB in endometriotic stromal cells.

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MeSH descriptors

Endometrium Interleukin-8 NF-kappa B Progesterone Progestins Tumor Necrosis Factor-alpha Endometrium Endometrium Endometrium Female Humans Interleukin-8 Interleukin-8 NF-kappa B NF-kappa B Progesterone Progestins Prospective Studies Stromal Cells Stromal Cells

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