[This corrects the article on p. 661 in vol. 17 PMCPMC6804327.].
BACKGROUND: The common causes of infertility in women with endometriosis are folliculogenesis alternation, steroidogenesis and fertilization impairment, oocyte and embryo quality reduction, and implantation defect. OBJECTIVE: To compare in…
BACKGROUND: Endometriosis is believed to be associated with dysfunction of the lymphocyte population and cytotoxicity of natural killer (NK) cells, induced by the production of interleukin-2 (IL-2). OBJECTIVE: This study aimed to investiga…
BACKGROUND: Endometriosis is associated with abnormal immunologic responses and combined inflammatory and anti-inflammatory conditions. OBJECTIVE: This study aims to investigate follicular fluid (FF) concentration of interleukin (IL)-3, IL…
BACKGROUND: Methylenetetrahydrofolate reductase enzyme (MTHFR) plays a key role in regulating folate balance, converting homocysteine to methionine, and producing s-adenosylmethionine (SAM) that plays a role in the methylation process. OBJ…
BACKGROUND: Endometriosis and infertility are caused by reactive oxygen species or free radicals, which promote endometrial cell growth and adhesion in the peritoneal cavity. Genistein has been proven to protect cells against reactive oxyge…
BACKGROUND: Endometriosis is a multifaceted gynecological disorder defined as a benign estrogen-dependent chronic inflammatory process in which endometrial glands and stroma-like tissues are located outside the uterine cavity. It affects ar…
Infertility negatively impacts the overall health and social life of affected individuals and couples. Female infertility is their inability to perceive pregnancy. To date, polycystic ovary syndrome, primary ovarian insufficiency, fallopian…
BACKGROUND: The relationship between the biochemical characteristics of follicular fluid (FF), oocyte quality and embryonic development has not yet been elucidated. We compared samples of FF with a normal metabolic profile against samples w…
BACKGROUND: According to stem cell theory, it seems that the proliferation/differentiation imbalance in endometrial mesenchymal stem cells (enMSCs) is the leading cause of endometriosis, so targeting them to modulate stemness-relevant facto…
BACKGROUND: Studies have evaluated different endometrial preparation methods, but the optimal frozen-thawed embryo transfer (FET) cycle strategy in terms of the in-vitro fertilization outcome is still debated. OBJECTIVE: To compare the nat…
BACKGROUND: The first case of inguinal endometriosis was described by Cullen. Endometriosis in the round ligament could be in the pelvic or inguinal area and is a rare disease occurring in 0.6% of women. Women with inguinal endometriosis ha…
BackgroundAlthough several studies have evaluated the risk of gynecological cancers in women with polycystic ovary syndrome (PCOS), there are controversies regarding it.ObjectiveThis study aimed to investigate the association of PCOS with e…
BACKGROUND: Endometriosis is one of the most common gynecological diseases and is associated with an increased risk of dyspareunia. OBJECTIVE: This study aimed to evaluate sexual self-efficacy (SSE) and sexual quality of life (SQOL) before…
Prenatal diagnosis of hereditary diseases has substantially altered the way medical geneticists are helping families affected by genetic disorders. However, the risk of miscarriage and fear of invasive diagnostic procedures may discourage m…
BACKGROUND: The role of glucocorticoids in implantation has been demonstrated. OBJECTIVE: This study aimed to evaluate the effect of dexamethasone on endometrial receptivity. MATERIALS AND METHODS: In this experimental study, 40 BALB/c fe…
BACKGROUND: Endometriosis pathogenesis is related to the inflammation shown by the secretion of pro-inflammatory mediators. This hypoxia condition can stimulate this condition. OBJECTIVE: To investigate the effect of hyperbaric oxygen ther…
BACKGROUND: Psychological consequences of infertility could have a negative effect on marital and sexual satisfaction. Numerous medical associations have strongly recommended psychological interventions, including counseling, to help infert…
BackgroundEmbryo quality may affect birth weight among neonates born through assisted reproductive technology. There are very limited studies assessing the adverse effect of transferring a poor-quality embryo with a good-quality one on neon…
BACKGROUND: Assisted reproductive technology treatments are stressful procedures, but there are individual differences in the emotional response to them. Differences in response to this stress may be related to the outcome of infertility tr…
BackgroundCerium dioxide nanoparticles (CNPs) due to the antidiabetic and antioxidant activities are proposed for the treatment of oxidative stress-associated diseases.ObjectiveTo examine the impact of CNPs on hyperglycemia-induced apoptosi…
BACKGROUND: Recurrent pregnancy loss (RPL) refers to the incidence of two or more abortions before the first half of pregnancy. Oxidative stress has been hypothesized to play a central role in RPL. OBJECTIVE: To investigate the relationshi…
BACKGROUND: Recurrent pregnancy loss (RPL) is the most common complaint of pregnancy in females with a prevalence of 5%. Numerous documents have shown that single nucleotide polymorphisms are able to change miRNA transcription and/or matura…
BACKGROUND: Lymphoid-tyrosine-phosphatase which is encoded by the protein tyrosine phosphatase non-receptor 22 (PTPN22) gene plays a pivotal role in the regulation of immune responses by dephosphorylating several signaling intermediates of …
BACKGROUND: Since progesterone alone does not seem to be enough for luteal phase support (LPS), especially in frozen embryo transfer (FET) cycles, so gonadotropin-releasing hormone agonist (GnRH-a) is suggested as an adjuvant therapy in com…