The relationship between coping strategies and infertility self-efficacy with pregnancy outcomes of women undergoing in vitro fertilization: A prospective cohort study

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This prospective cohort study of 154 women undergoing in vitro fertilization found no significant relationship between coping strategies, infertility self-efficacy, and pregnancy outcomes.

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This prospective cohort study evaluated the impact of coping strategies and infertility self-efficacy on pregnancy outcomes in 154 women undergoing in vitro fertilization or intracytoplasmic sperm injection. Researchers administered psychological assessments at the start of ovarian stimulation and prior to embryo transfer, ultimately analyzing data from 88 participants who reached the transfer stage. The results indicated no statistically significant differences in coping mechanisms or self-efficacy levels between women who achieved clinical pregnancy and those who did not. This paper is centrally about endometriosis — specifically, it excludes patients with severe endometriosis as an inclusion criterion to isolate the effects of psychological factors on IVF success.

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Abstract

BACKGROUND: Assisted reproductive technology treatments are stressful procedures, but there are individual differences in the emotional response to them. Differences in response to this stress may be related to the outcome of infertility treatment. OBJECTIVE: This study aimed to investigate the relationship between coping strategies and infertility self-efficacy with pregnancy outcomes of women undergoing in vitro fertilization/intracytoplasmic sperm injection treatment. MATERIALS AND METHODS: This was a prospective cohort study and the 154 infertile women were psychologically evaluated in 2 stages: once before ovarian stimulation and again during embryo transfer. The research measurements used were the Revised COPE, the Depression Anxiety Stress Scale (DASS-21) and the Infertility Self-Efficacy Scale. RESULTS: There was no significant difference between the group of non-pregnant women and the positive pregnancy group in terms of coping strategies (mental rumination, self-blame, active confronting, goal replacement, avoidance) or self-efficacy in either of the 2 stages of ovarian stimulation and embryo transfer. The Mann-Whitney test did not show any statistical difference between the clinically pregnant women and the only laboratory positive pregnant group. Moreover, the self-blame and mental rumination strategies were positively related with anxiety and depression. Conversely, active confronting, goal replacement, avoidance and self-efficacy were associated with decreased depression, anxiety and stress levels. CONCLUSION: It can be concluded that there is no relationship between coping strategies and infertility self-efficacy with in vitro fertilization/intracytoplasmic sperm injection outcomes. Further research is needed to clarify the effects of other psychological factors on the pregnancy outcomes of assisted reproductive treatment.
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The results of this study showed that there was no relationship between coping strategies and ISE with the pregnancy outcomes of IVF/ICSI treatment. In addition, recent studies have shown that the effects of psychological distress on IVF treatment outcomes are not yet clear, and women's emotional distress does not appear to determine the success of treatment through ART. It can be concluded that the relationship between psychological factors and IVF outcomes is more complex than is usually thought.

Coi Statement

The authors declare that there is no conflict of interest.

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infertility

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europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
pubmed
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