Study types
- article 19
- other 2
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Condition tags
- endometriosis 22
- dysmenorrhea 2
- infertility 2
- chronic_pelvic_pain 1
- endometrioma 1
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Frequent coauthors
- Fukaya T 18
- Nagamasa Maeda 13
- Chiaki Izumiya 12
- Izumiya C 10
- Maeda N 10
- Yorito Yamamoto 9
- Yamamoto Y 8
- Hiroyoshi Oguri 7
- Akira Yajima 7
- Kusume T 7
STUDY QUESTION: Does the GnRH antagonist, ASP1707, reduce endometriosis-associated pelvic pain? SUMMARY ANSWER: ASP1707 significantly reduced endometriosis-associated pelvic pain in a dose-related manner. WHAT IS KNOWN ALREADY: GnRH agonist…
Increased killer inhibitory receptor 2DL1 expression among natural killer cells in women with pelvic endometriosis
Objective: To evaluate the management of young women with endometriosis after conservative laparoscopic surgery.Design: Retrospective study.Setting: Department of Obstetrics and Gynecology, Kochi Medical School.Patients: Sixty-four women ag…
Impaired natural killer (NK) activity in women with endometriosis is thought to promote implantation and progression of endometrial tissue, in accord with Sampson's hypothesis. However, the mechanisms responsible for decreased NK cell activ…
Objective: To evaluate the efficacy of laparoscopic surgery for endometriosis-associated infertility.Design: Retrospective study.Setting: Department of Obstetrics and Gynecology, Kochi Medical School.Patient(s): Sixty-five women with endome…
OBJECTIVE: To investigate menstrual cycle changes in expression by eutopic endometrium of a nonclassic human leukocyte antigen, HLA-G, which binds to the killer immunoglobulin-like receptor (KIR) 2DL4 (CD158d) on natural killer (NK) cells. …
ObjectiveTo investigate the macrophage response in endometriosis by determining the expression and localization of human leukocyte antigen (HLA)-ABC and HLA-DR by the peritoneal fluid (PF) macrophages and PF concentrations of interferon (IF…
PROBLEM: We investigated host immunologic responses to endometriosis by comparing immune cell surface antigens in peripheral blood (PB) and peritoneal fluid (PF) from women with endometriosis with those in PB and PF from other patients. MET…
PROBLEM: We investigated inhibitory and activation motif expression of killer immunoglobulin-like receptor (KIR) by natural killer (NK) cells, which may be pathogenetically involved in endometriosis. METHOD OF STUDY: We compared cells from…
ObjectiveTo investigate the macrophage response in endometriosis, we determined expression of human leukocyte antigen (HLA)-ABC, HLA-DR, and their costimulatory molecules by peritoneal fluid (PF) macrophages.DesignCase-control study of immu…
PROBLEM: Natural killer (NK) dysfunction is considered to contribute to the pathogenesis of endometriosis. In this study, we investigated the host immune response to endometriosis in terms of killer inhibitory receptor (KIR) expression by N…
ObjectiveTo investigate the macrophage response in endometriosis, we determined the expression of human leukocyte antigen (HLA)-DR, intercellular adhesion molecule (ICAM)-1, and CD14 on peritoneal macrophages.DesignCase-control study of imm…
ObjectiveTo investigate host immunologic response to endometriosis in terms of intercellular adhesion molecule (ICAM)-1 expression by macrophages and killer cell inhibitory receptor (KIR) expression by natural killer (NK) cells.DesignCase-c…
ObjectiveTo investigate the host immunologic response to endometriosis in terms of killer inhibitory receptor (KIR) expression by natural killer (NK) cells.DesignCase-control study of immunologic markers.SettingUniversity hospital.Patient(s…
ObjectiveTo evaluate the expression of estrogen receptor (ER)-alpha and ER-beta messenger RNA (mRNA) in ovarian endometriosis.DesignProspective study.SettingUniversity hospital.Patient(s)Patients with endometriosis and patients with uterine…
PROBLEM: Factors regulating fibrosis in peritoneal endometriosis are poorly understood. We hypothesized that mast cell proteases may play a role in the process of fibrosis in peritoneal endometriosis. As the first step in examining the poss…
ObjectiveWe evaluated the secretion of hepatocyte growth factor by eutopic endometrial stromal cells in vitro.DesignEutopic endometrial stromal cells were isolated and the culture supernatants were collected after 48 hours of incubation. Th…
The clinical and pathological features of an apparently unique case of an endometrial cyst of the uterus are reported. The cyst was located within the myometrium of a 16-year-old woman suffering from dysmenorrhea. After excision of the cyst…
Among the women who suffered from endomertiosis, pelvic adhesion and polycystic ovarian deseas were treated by endosopic approach to evaluate the effectiveness and consequent pregnancy rate after endoscopic treatment. For endoscopic incisio…
FUKAYA, T., SUGAWARA, J., YOSHIDA, H. and YAJIMA, A. The Role of Macrophage Colony Stimulating Factor in the Peritoneal Fluid in Infertile Patients with Endometriosis. Tohoku J. Exp. Med., 1994, 172 (3), 221-226-Macrophage colony stimulatin…
ObjectiveTo establish a relationship between pelvic pain and the stage and severity of pelvic endometriosis determined according to the revised American Fertility Society classification.Study designRetrospective study of 618 cases diagnosed…
ObjectiveTo clarify the pathogenesis of endometriosis on the basis of analysis of primary lesion sites, age at onset, rate of progression, and response to drug treatment.Study designThe clinical records of 690 women with laparoscopically co…