Efficacy of laparoscopic surgery for endometriosis-associated infertility

In: JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY · 2010 · vol. 26(2) , pp. 511–515 · doi:10.5180/jsgoe.26.511 · W2326022775
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Laparoscopic surgery for endometriosis-associated infertility resulted in a 59.6% clinical pregnancy rate, with most pregnancies occurring spontaneously within one year.

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This retrospective study evaluated laparoscopic evaluation and treatment outcomes in 65 women with endometriosis-associated infertility, with clinical pregnancy rates assessed among 57 followed for more than 6 months. After surgery, 34 of 57 conceived for a clinical pregnancy rate of 59.6%, with 28 non-ART pregnancies and 8 and 80% of non-ART conceptions occurring within 1 year. Pregnancy rates differed by disease severity (61.1% non-ART in minimal/mild versus 43.8% in moderate/severe) and by age (<35 years 67.6% versus older 27.2%). A key limitation is the retrospective design and reliance on follow-up and outcome measures described at the clinic level. This paper is centrally about endometriosis — it assesses the efficacy of laparoscopic surgery for endometriosis-associated infertility and resulting conception rates.

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Abstract

Objective: To evaluate the efficacy of laparoscopic surgery for endometriosis-associated infertility.Design: Retrospective study.Setting: Department of Obstetrics and Gynecology, Kochi Medical School.Patient(s): Sixty-five women with endometriosis-associated infertility.Intervention(s): Laparoscopic evaluation and treatment of endometriosis.Main outcome Measure(s): Background of 65 women with endometriosis-associated infertility. Clinical pregnancy rate (PR) of 57 women, who were followed > 6 months after laparoscopic surgery for endometriosis.Result: Of 57 women who underwent laparoscopic surgery, 34 conceived (clinical PR, 59.6%), including 28 non-ART pregnancies and 6 ART pregnancies. Eighty percent of non-ART pregnancies conceived within 1 year after laparoscopic surgery. In women with minimal and mild endometriosis, the clinical PR of non-ART after laparoscopic surgery was 61.1%, and in women with moderate and severe endometriosis the clinical PR of non-ART was 43.8%. The clinical PR of non-ART in women < 35 years of age (67.6%) was significantly higher than in older women (27.2%).Conclusion: Women with endometriosis-associated infertility can be expected to conceive spontaneously within 1 year after laparoscopic surgery. When patients fail to conceive 1 year after laparoscopic surgery, ART should be considered.
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Abstract

Objective: To evaluate the efficacy of laparoscopic surgery for endometriosis-associated infertility. Design: Retrospective study. Setting: Department of Obstetrics and Gynecology, Kochi Medical School. Patient(s): Sixty-five women with endometriosis-associated infertility. Intervention(s): Laparoscopic evaluation and treatment of endometriosis. Main outcome Measure(s): Background of 65 women with endometriosis-associated infertility. Clinical pregnancy rate (PR) of 57 women, who were followed > 6 months after laparoscopic surgery for endometriosis.

Result

Of 57 women who underwent laparoscopic surgery, 34 conceived (clinical PR, 59.6%), including 28 non-ART pregnancies and 6 ART pregnancies. Eighty percent of non-ART pregnancies conceived within 1 year after laparoscopic surgery. In women with minimal and mild endometriosis, the clinical PR of non-ART after laparoscopic surgery was 61.1%, and in women with moderate and severe endometriosis the clinical PR of non-ART was 43.8%. The clinical PR of non-ART in women < 35 years of age (67.6%) was significantly higher than in older women (27.2%).

Conclusion

Women with endometriosis-associated infertility can be expected to conceive spontaneously within 1 year after laparoscopic surgery. When patients fail to conceive 1 year after laparoscopic surgery, ART should be considered. Design: Retrospective study. Setting: Department of Obstetrics and Gynecology, Kochi Medical School. Patient(s): Sixty-five women with endometriosis-associated infertility. Intervention(s): Laparoscopic evaluation and treatment of endometriosis. Main outcome Measure(s): Background of 65 women with endometriosis-associated infertility. Clinical pregnancy rate (PR) of 57 women, who were followed > 6 months after laparoscopic surgery for endometriosis.

Result

Of 57 women who underwent laparoscopic surgery, 34 conceived (clinical PR, 59.6%), including 28 non-ART pregnancies and 6 ART pregnancies. Eighty percent of non-ART pregnancies conceived within 1 year after laparoscopic surgery. In women with minimal and mild endometriosis, the clinical PR of non-ART after laparoscopic surgery was 61.1%, and in women with moderate and severe endometriosis the clinical PR of non-ART was 43.8%. The clinical PR of non-ART in women < 35 years of age (67.6%) was significantly higher than in older women (27.2%).

Conclusion

Women with endometriosis-associated infertility can be expected to conceive spontaneously within 1 year after laparoscopic surgery. When patients fail to conceive 1 year after laparoscopic surgery, ART should be considered. © 2010 Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy Favorites & Alerts Recently viewed articles

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endometriosisinfertility

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