Clinical characteristics indicating adenomyosis at the time of hysterectomy: a retrospective study in 291 patients

Taran FA, F Andrei Taran, Florin‐Andrei Taran, Markus Wallwiener, Drita Kabashi, Kabashi D, Ralf Rothmund, Rothmund R, Katharina Rall, Rall K, Kraemer B, Bernhard Kraemer, Sara Y Brucker, Brucker SY
Archives of gynecology and obstetrics · 2011 · vol. 285(6) , pp. 1571–1576 · doi:10.1007/s00404-011-2180-7 · PMID:22193824 · W2075405910
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-12 ⓘ

Adenomyosis in hysterectomy patients was characterized by younger age, lower uterine weight, and more disease-specific symptoms, with pelvic pain, smoking, and prior delivery associated with increased likelihood.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This retrospective study reviewed medical records of 291 women undergoing hysterectomy with histologic diagnoses of adenomyosis alone, adenomyosis with leiomyomas, or leiomyomas alone. In univariate analyses, women with adenomyosis were younger, had lower uterine weights, and reported more disease-specific symptoms. Multinomial logistic regression found that lower uterine weight, pelvic pain, history of smoking, and at least one delivery were associated with a greater likelihood of adenomyosis rather than leiomyomas alone. The paper’s conclusions are limited by its retrospective design and restriction to patients who ultimately underwent hysterectomy. This paper does not explicitly discuss endometriosis; it focuses on adenomyosis at hysterectomy, so it relates to adenomyosis by characterizing clinical features associated with histologically confirmed adenomyosis.

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Abstract

PurposeTo better characterize adenomyosis as a disease entity.MethodsWe retrospectively reviewed the medical records of women undergoing hysterectomy with a histologic diagnosis of adenomyosis, adenomyosis and leiomyomas, and leiomyomas alone.ResultsThe study included 291 women: 38 with adenomyosis alone, 56 with adenomyosis and leiomyomas, and 197 with leiomyomas alone. In univariate analysis, women with adenomyosis were younger (p = 0.018) and had lower uterine weights (p < 0.001) and more disease-specific symptoms (p = 0.008). In multinomial logistic regression analysis, a lower uterine weight (OR 0.99, CI 95% 0.99-1.0), pelvic pain (OR 4.8, CI 95% 1.5-15.2), a history of smoking (OR 2.6, CI 95% 1.1-6.5) and at least one delivery (OR 4.3, CI 95% 1.5-12.3) were associated with a greater likelihood of having adenomyosis but not leiomyomas alone.ConclusionsWomen undergoing hysterectomy with adenomyosis alone have different clinical characteristics from women with adenomyosis and leiomyomas and from those with only leiomyomas.
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Abstract

Purpose To better characterize adenomyosis as a disease entity.

Methods

We retrospectively reviewed the medical records of women undergoing hysterectomy with a histologic diagnosis of adenomyosis, adenomyosis and leiomyomas, and leiomyomas alone.

Results

The study included 291 women: 38 with adenomyosis alone, 56 with adenomyosis and leiomyomas, and 197 with leiomyomas alone. In univariate analysis, women with adenomyosis were younger (p = 0.018) and had lower uterine weights (p < 0.001) and more disease-specific symptoms (p = 0.008). In multinomial logistic regression analysis, a lower uterine weight (OR 0.99, CI 95% 0.99–1.0), pelvic pain (OR 4.8, CI 95% 1.5–15.2), a history of smoking (OR 2.6, CI 95% 1.1–6.5) and at least one delivery (OR 4.3, CI 95% 1.5–12.3) were associated with a greater likelihood of having adenomyosis but not leiomyomas alone.

Conclusions

Women undergoing hysterectomy with adenomyosis alone have different clinical characteristics from women with adenomyosis and leiomyomas and from those with only leiomyomas. Similar content being viewed by others

References

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Condition tags

endometriosischronic_pelvic_painadenomyosis

MeSH descriptors

Endometriosis Hysterectomy Adult Endometriosis Endometriosis Female Humans Hysterectomy Leiomyoma Leiomyoma Leiomyoma Middle Aged Organ Size Pelvic Pain Pelvic Pain Pelvic Pain Retrospective Studies Risk Factors Smoking Smoking

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