{"paper_id":"fce3d77b-61dc-460b-9efa-a5147d02bc62","body_text":"Abstract\nPurpose\nTo better characterize adenomyosis as a disease entity.\nMethods\nWe retrospectively reviewed the medical records of women undergoing hysterectomy with a histologic diagnosis of adenomyosis, adenomyosis and leiomyomas, and leiomyomas alone.\nResults\nThe study included 291 women: 38 with adenomyosis alone, 56 with adenomyosis and leiomyomas, and 197 with leiomyomas alone. In univariate analysis, women with adenomyosis were younger (p = 0.018) and had lower uterine weights (p < 0.001) and more disease-specific symptoms (p = 0.008). In multinomial logistic regression analysis, a lower uterine weight (OR 0.99, CI 95% 0.99–1.0), pelvic pain (OR 4.8, CI 95% 1.5–15.2), a history of smoking (OR 2.6, CI 95% 1.1–6.5) and at least one delivery (OR 4.3, CI 95% 1.5–12.3) were associated with a greater likelihood of having adenomyosis but not leiomyomas alone.\nConclusions\nWomen undergoing hysterectomy with adenomyosis alone have different clinical characteristics from women with adenomyosis and leiomyomas and from those with only leiomyomas.\nSimilar content being viewed by others\nReferences\nFerenczy A (1998) Pathophysiology of adenomyosis. Hum Reprod Update 4(4):312–322\nAzziz R (1989) Adenomyosis: current perspectives. Obstet Gynecol Clin North Am 16(1):221–235\nWalker CL, Stewart EA (2005) Uterine fibroids: the elephant in the room. 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