Adenomyosis and Pain

Adenomyosis affects about 20% of women of reproductive age and is responsible for menorrhagia, dysmenorrhea, menstrual pelvic pain, dyspareunia, and infertility [1]. The causes of adenomyosis-related pain are unclear. When combined with endometriosis, especially deep infiltrating endometriosis (DIE), dysmenorrhea is more severe in patients with adenomyosis, and the chance of progressive dysmenorrhea will increase. Other pain mechanisms related to adenomyosis include abnormal uterine contractility and abnormal expression of the oxytocin receptor (OTR), abnormal expression of prostaglandin (PG) and cyclooxygenase 2 (COX-2), abnormal growth and distribution of local nerve fibers, neuropeptides, macrophages, abnormal secretion of cells and inflammatory factors, and so on. There may still be some unknown mechanisms that need further study and research. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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