The Clinical Features and Diagnosis of Adenomyosis
This chapter will discuss the clinical features and diagnosis of adenomyosis, a condition historically diagnosed post-hysterectomy but now increasingly identified in young women due to advancements in imaging.
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This chapter reviews the clinical features and diagnosis of adenomyosis, describing how the condition was historically underrecognized because it was often diagnosed only on hysterectomy histology in reproductive-age women with heavy bleeding or pelvic pain, with incidence and prevalence varying by diagnostic criteria. It notes that in the past decade, imaging advancements have enabled adenomyosis diagnosis in younger reproductive-age women, but there remains poor clinical awareness, limited consensus on definition, and a lack of standardized classification. It also highlights that adenomyosis is frequently associated with other gynecologic conditions such as endometriosis and fibroids, which complicates diagnostic interpretation. Relevance to endometriosis: adenomyosis is repeatedly discussed in relation to endometriosis (including historical framing by Cullen and mention of frequent coexistence/association), though the chapter’s main focus is clinical features and diagnostic approaches for adenomyosis.
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