Uterine adenomyosis: pathogenesis, diagnostics, symptomatology and treatment.
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This review analyzes the etiology, diagnostics, classification, treatment, and fertility implications of adenomyosis, a condition characterized by endometrial glands in the myometrium.
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Abstract
OBJECTIVE: To summarize the current knowledge about pathogenesis, diagnostics, symptomatology and the treatment of adenomysis. DESIGN: Review article. SETTING: The Centre of Assisted Reproduction, ISCARE I.V.F., Prague. METHODS: Analysis of literature and current studies. RESULTS: This article reviews etiology, diagnostics and classification of adenomyosis, medical and surgical management options and the fertility implication of adenomyosis. CONCLUSION: Uterine adenomyosis is characterized by the presence of endometrial glands in myometrium and usually manifests by pelvic pain, abnormal uterine bleeding or infertility. Although adenomyosis and endometriosis share a number of features, they are considered to be two different entities. Recent improvements of imaging techniques such as transvaginal ultrasound and magnetic resonance imaging have affected the detection of adenomyosis. Adenomyosis has a negative impact on IVF results.
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Cited by (27)
- Oestrogen promotes the progression of adenomyosis by inhibiting CITED2 through miR-145 2024
- Clinical application of a simplified hysteroscopic LNG-IUD non-suture fixation in the treatment of adenomyosis 2024
- Pregnancy outcomes in women with adenomyosis, undergoing artificial endometrial preparation with and without gonadotropin-releasing hormone agonist pretreatment in frozen embryo transfer cycles: An RCT 2023
- Influence of assisted reproductive technology and uterine leiomyoma on pregnancy outcomes in women with adenomyosis 2023
- Magnetic Resonance Roadmap in Detecting and Staging Endometriosis: Usual and Unusual Localizations 2023
- MIR503HG silencing promotes endometrial stromal cell progression and metastasis and suppresses apoptosis in adenomyosis by activating the Wnt/β‑catenin pathway via targeting miR‑191 2023
- Pregnancy outcomes of 4 endometrial preparation protocols in adenomyosis patients with thin endometrium during frozen embryo transfer: a retrospective cohort study 2023
- Presence of Adenomyosis Impairs Clinical Outcomes in Women Undergoing Frozen Embryo Transfer: A Retrospective Cohort Study 2023
- Endometrial cell‑derived exosomes facilitate the development of adenomyosis via the IL‑6/JAK2/STAT3 pathway 2023
- Unveiling the Pathogenesis of Adenomyosis through Animal Models 2022
- Efficacy of high-intensity focused ultrasound combined with LNG-IUS for adenomyosis: a systematic review and meta-analysis 2022
- Abnormal uterine bleeding: etiology and pathogenesis (descriptive review) 2022
- Exploration the global single-cell ecological landscape of adenomyosis-related cell clusters by single-cell RNA sequencing 2022
- Secondary cystic adenomyosis in a young woman: a case report 2022
- Uterine adenomyotic cyst with markedly elevated serum CA19‑9 and CA125 levels: A case report 2022
- Possible association between adenomyosis and disseminated intravascular coagulation and thromboembolism: A systematic review 2022
- Molecular Targets for Nonhormonal Treatment Based on a Multistep Process of Adenomyosis Development 2022
- Endometrial stromal cell proteomic analysis reveals LIM and SH3 protein 1 (LASP1) plays important roles in the progression of adenomyosis 2021
- The Clinical Features and Diagnosis of Adenomyosis 2021
- Endometriosis - Recent Advances, New Perspectives and Treatments 2021
- Optimization of diagnostic studies in patients with adenomiosis and/or hyperplastic processes of endometrium 2021
- Celecoxib reduces inflammation and angiogenesis in mice with adenomyosis. 2021
- Talin1 Induces Epithelial-Mesenchymal Transition to Facilitate Endometrial Cell Migration and Invasion in Adenomyosis Under the Regulation of microRNA-145-5p 2021
- Maternal–Fetal Outcomes in Women with Endometriosis and Shared Pathogenic Mechanisms 2021
- Down-regulated miR-124-3p enhanced the migration and epithelial-stromal transformation of endometrial stromal cells extracted from eutopic endometrium in subjects with adenomyosis by up-regulating Neuropilin 1 2020
- Immunohistochemical features of benign endometrial hyperplasia in premenopausal women 2020
- АНАЛІЗ КЛІНІКО-АНАМНЕСТИЧНИХ ДАНИХ І ПРЕМОРБІДНОГО ФОНУ ПРИ АДЕНОМІОЗІ 2020
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