Influence of assisted reproductive technology and uterine leiomyoma on pregnancy outcomes in women with adenomyosis

Yiling Wang, Zhao Tian, Xiaohong Chang, Hong-Lan Zhu, Heng Cui
In: Gynecology and Obstetrics Clinical Medicine · 2023 · vol. 3(1) , pp. 56–59 · doi:10.1016/j.gocm.2023.01.008 · W4320915141
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Assisted reproductive technology increased hypertensive disorders and postpartum hemorrhage in women with adenomyosis, while large uterine leiomyomas further raised the risk of severe postpartum hemorrhage.

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Abstract

Abstract Aim To assess whether adverse pregnancy outcomes in women with adenomyosis are different according to the method of conception and the concurrent of uterine leiomyoma (UL). Methods We performed a retrospective study. Fifty-three singleton pregnancy cases complicated with adenomyosis were included in this study. In the study group, 15 women became pregnant with assisted reproductive technology (ART) and 21 women combined with UL. Pregnancy outcomes were compared between ART and non-ART, UL and non-UL groups. Results The prevalence for such complications as hypertensive disorder complicating pregnancy (HDCP)and postpartum hemorrhage (PPH)were significantly higher in the women conceived by ART (33.3% vs. 5.3%, P ​= ​0.023) and (53.3% vs. 23.7%, P ​= ​0.037),respectively. And women concurrent with UL of which the diameter≥4 ​cm were more likely to have severe PPH (44.4% vs. 0%, P ​= ​0.021). Conclusion ART may increase the risk of adverse pregnancy outcomes such as HDCP and PPH in women with adenomyosis and UL of which the diameter≥4 ​cm may further increase the risk of severe PPH.

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adenomyosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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