Comprehensive method of ultrasound diagnosis of adenomyosis

Stanislava V. Nagorneva, Maria A. Shalina, Maria I. Yarmolinskaya, Elena A. Netreba
In: Journal of obstetrics and women's diseases · 2021 · vol. 70(6) , pp. 73–82 · doi:10.17816/jowd83066 · W4210671567
article OA: closed CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

A comprehensive ultrasound method using six techniques and a scoring system demonstrated 95% sensitivity and 100% specificity for diagnosing adenomyosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This original study evaluated the diagnostic capabilities of ultrasound for diffuse adenomyosis in 164 patients aged 22–43 using a developed scoring system and six sequential ultrasound techniques. Methods included assessing myometrial echostructure homogeneity, anterior/posterior uterine wall thickness ratio, compression elastography, junctional zone evaluation in 3D, uniformity of junctional zone thickness, and myometrial vascularization by Power Doppler 3D Glass Body, with summed criterion scores used to determine presence and severity. The authors reported sensitivity of 95%, specificity of 100%, positive predictive value of 100%, negative predictive value of 90%, and overall accuracy of 97%. This paper is centrally about endometriosis and adenomyosis — it specifically focuses on ultrasound diagnosis of adenomyosis and does not address endometriosis.

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Abstract

BACKGROUND: There are currently no uniform standards for adenomyosis diagnosis, so the search for the most informative methods is an urgent task. This article presents modern views on the diagnosis of adenomyosis and the role of ultrasound in its diagnostics. AIM: The aim of this study was to determine the diagnostic capabilities of ultrasound in the diffuse form of adenomyosis. MATERIALS AND METHODS: This study included 164 patients aged 22 to 43 years old, who had a comprehensive ultrasound examination done. The points were calculated and the presence or absence of adenomyosis, as well as its severity, were determined using the developed scale. The sequential implementation of six ultrasound techniques were used for a comprehensive ultrasound assessment of adenomyosis: assessment of the myometrium echostructure homogeneity; assessment of the ratio of the anterior and posterior uterine wall thicknesses; compression elastography; assessment of the junctional zone in the 3D mode; assessment of the uniformity of the junctional zone thickness along uterine walls; vascularization of the myometrium in the Power Doppler 3D Glass Body mode. RESULTS: We have developed the comprehensive ultrasound method of adenomyosis diagnostics. The sensitivity of the method was 95%, and the specificity was 100%. The positive predictive value was 100%, and the negative predictive value was 90%. The accuracy of the method was 97%. CONCLUSIONS: The developed scoring system for the comprehensive assessment of adenomyosis allows for an independent assessment of the myometrium for each criterion, summarizing the scores and, therefore, assessing the presence and severity of adenomyosis more objectively and reliably. The high sensitivity and specificity of this technique allows recommending it for use by ultrasound specialists.

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adenomyosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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