Subendometrial and intraendometrial blood flow during the menstrual cycle in patients with endometriosis
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This study investigated subendometrial and intraendometrial blood flow patterns throughout the menstrual cycle in patients diagnosed with endometriosis.
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Abstract
ObjectiveTo use power Doppler ultrasound to assess the effect of endometriosis on intraendometrial and subendometrial blood flow during the menstrual cycle.DesignAn observational prospective study.SettingAcademic teaching hospital.Patient(s)Thirty patients with histologically confirmed ovarian endometrioma and 15 control women.Intervention(s)Power Doppler ultrasound examination during the menstrual cycle.Main outcome measure(s)Intraendometrial and subendometrial color signals assessed by power Doppler ultrasound.Result(s)A statistically significant higher proportion of endometrioma patients presented simultaneous intraendometrial and subendometrial color signals in the late secretory cycle phase compared with controls (40.0% vs. 6.7%).Conclusion(s)The higher endometrial perfusion in patients with ovarian endometrioma that is observed in the late secretory phase of the cycle, close to menstrual shedding, favors the hypothesis that women with endometriosis might have higher endometrial vascular activity, thus facilitating the implantation process of endometrial cells outside the uterus.
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Cited by (14)
- A Temporal Mechanism-Based Framework of Endometriosis Affecting Pregnancy Outcomes 2026
- Role and mechanism of mesenchymal stem cells in endometrial receptivity remodeling 2026
- Histopathologic characteristics of term placentas in singleton pregnancies in women with endometriosis-related infertility after ART treatment: case-control study 2024
- The Performance of the Uterine Artery Resistance Index following Stimulation of the Cervix in the Diagnosis of Endometriosis: A Prospective Study 2022
- CONTROVERSIAL ISSUES OF RADIOLOGIC DIAGNOSIS OF ADENOMYOSIS IN REPRODUCTIVE LOSSES 2019
- Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis 2019
- Utero-ovarian hemodynamics after laparoscopic treatment of infertility caused by moderate to severe endometriosis 2013
- Defective myometrial spiral artery remodelling as a cause of major obstetrical syndromes in endometriosis and adenomyosis 2012
- Vascular endothelial growth factor expression up-regulated by endometrial ischemia in secretory phase plays an important role in endometriosis 2011
- Endometriosis, a modern syndrome. 2011
- Adenomyosis: New Knowledge is Generating New Treatment Strategies 2009
- Uterine adenomyosis: a need for uniform terminology and consensus classification 2008
- Endometriosis is associated with a decreased risk of pre-eclampsia 2007
- Differential infiltration of macrophages and prostaglandin production by different uterine leiomyomas 2006
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