Pregnancy and symptomatic relief following ultrasound‐guided transvaginal radiofrequency ablation in patients with adenomyosis

Jang‐Hyun Nam
Journal of Obstetrics and Gynaecology Research · 2019 · vol. 46(1) , pp. 124–132 · doi:10.1111/jog.14145 · PMID:31646731 · W2982115827
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Ultrasound-guided transvaginal radiofrequency ablation in adenomyosis patients resulted in a 50% pregnancy success rate and significantly reduced blood loss and pain scores post-procedure.

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Abstract

AIM: To report the reproductive results and symptomatic relief of patients with adenomyosis who attempted to conceive after ultrasound-guided radiofrequency ablation (RFA). METHODS: Of 182 consecutive patients with adenomyosis who had undergone RFA, only 81 patients were eligible for this study. Pregnancy outcomes, postoperative complications, preoperative and postoperative pictorial blood loss assessment chart scores, and pain scores were evaluated. RESULTS: Of these 81 patients, 74 were infertile and seven were single at the time of RFA. The mean age at the time of operation was 35.8 years. The mean duration from the time of RFA to conception was 18.9 months (range, 2-72 months). Fifty-nine patients tried natural conception, while 22 patients attempted conception with assisted reproductive techniques. Twenty-nine (35.8%) patients achieved 39 pregnancies. Except for the 23 patients who did not actively try to conceive and who inevitably or arbitrarily discontinued pregnancy attempts, the pregnancy success rate reached 50%. Twenty-two (84.6%) of the 29 patients delivered 24 (66.7%) live babies (nine vaginal deliveries and 15 cesarean sections). Twelve (33.3%) pregnancies ended in spontaneous abortions. No uterine ruptures occurred. Paired sample t-tests revealed that preoperative pictorial blood loss assessment chart and pain scores were significantly (P < 0.05) different from the postoperative scores at 1-, 3- and 6-months. CONCLUSION: RFA could be considered a minimally-invasive treatment option for patients with adenomyosis who desire to maintain fertility and alleviate symptoms.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis High-Intensity Focused Ultrasound Ablation Infertility, Female Radiation Injuries Radiofrequency Ablation Adenomyosis Adult Female Fertility Preservation Fertility Preservation Fertilization Fertilization High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation Humans Infertility, Female Infertility, Female Pregnancy Pregnancy Outcome Pregnancy Rate

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