Laparoscopic Radiofrequency Thermal Ablation for Uterine Adenomyosis

Stefano Scarperi, Giovanni Pontrelli, C Campana, Colette Campana, Martin Steinkasserer, Alfredo Ercoli, Luca Minelli, Valentino Bergamini, Marcello Ceccaroni
JSLS : Journal of the Society of Laparoendoscopic Surgeons · 2015 · vol. 19(4) , pp. e2015.00071 · doi:10.4293/jsls.2015.00071 · PMID:26648676 · W2408793138
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Laparoscopic radiofrequency thermal ablation significantly reduced uterine adenomyosis volume and improved patient symptoms over a 12-month follow-up period.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This prospective study evaluated the feasibility and efficacy of laparoscopic radiofrequency thermal ablation in 15 premenopausal women with symptomatic nodular uterine adenomyosis who declined hysterectomy and had lesions confirmed on biopsy, using transvaginal ultrasonography at baseline and 3, 6, 9, and 12 months plus dysmenorrhea assessment by visual analog scale. The authors report no intra- or postoperative complications, with progressive reductions in adenomyosis volume (median ~32% at 3 months to ~65% at 12 months) and significant symptom improvement (median VAS dropping from ~9 to ~2.6 at 12 months, with 80% of those completing 1 year reporting VAS ≤3). The main limitations explicitly acknowledged include short follow-up and the broader field lacking evidence-based guidelines for minimally invasive adenomyosis treatments compared with hysterectomy. This paper is centrally about endometriosis and/or adenomyosis — it is focused specifically on laparoscopic radiofrequency thermal ablation for uterine adenomyosis.

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Abstract

BACKGROUND AND OBJECTIVES: Symptomatic uterine adenomyosis, unresponsive to medical therapy, is a challenging condition for patients who desire to preserve their uterus. This study was an evaluation of the feasibility and efficacy of laparoscopic radiofrequency thermal ablation of symptomatic nodular uterine adenomyosis. METHODS: Fifteen women with symptomatic nodular adenomyosis, who had no plans for pregnancy but declined hysterectomy, underwent radiofrequency thermal ablation. Ultrasonography was performed at baseline and at postoperative follow-ups at 3, 6, 9, and 12 months. The impact of uterine adenomyosis-related symptoms was assessed according to the visual analog scale. RESULTS: The median number of nodular lesions treated per patient was 1 (range, 1-2). The median baseline volume of the adenomyosis area was 60 cm(3) (range, 18-128). The median reduction in volume was 32, 49.4, 59.6, and 65.4% at 3, 6, 9, and 12 months, respectively. A significant progressive improvement in the symptoms score was observed at the 4 follow-ups. CONCLUSION: In this study, laparoscopic radiofrequency thermal ablation reduced uterine adenomyosis-related symptoms and volume, with significant relief of symptoms.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Catheter Ablation Laparoscopy Adenomyosis Adenomyosis Adult Feasibility Studies Female Follow-Up Studies Humans Middle Aged Ultrasonography Visual Analog Scale

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