Uterine artery embolization for adenomyosis without fibroids

MD Kim, M D Kim, Kim MD, Won JW, Jong-Jin Won, J W Won, Lee DY, D Y Lee, C.-S Ahn, Ahn CS
Clinical Radiology · 2004 · vol. 59(6) , pp. 520–526 · doi:10.1016/j.crad.2003.11.018 · PMID:15145722 · W2048920019
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This study evaluated the safety and effectiveness of uterine artery embolization (UAE) for treating adenomyosis in women without uterine fibroids.

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Abstract

AimTo evaluate the potential usefulness of transcatheter uterine artery embolization as a treatment for symptomatic adenomyosis in patients without uterine fibroids.Materials and methodsUterine artery embolization using polyvinyl alcohol particles sized 250-710 mm was performed in 43 patients (mean; 40.3 years, range; 31-52 years) with dysmenorrhoea, menorrhagia, or bulk-related symptoms (pelvic heaviness, urinary frequency) due to adenomyosis without fibroids. All patients underwent pre-procedural and 3.5 months (range 1-8 months) follow-up magnetic resonance imaging (MRI) with contrast enhancement. Clinical symptoms were also assessed at the time of MRI before and after embolization.ResultsSignificant improvement of dysmenorrhoea (95.2%) and menorrhagia (95.0%) was reported in most patients. Contrast-enhanced MRI revealed non-enhancing areas suggesting coagulation necrosis of adenomyosis in 31 patients (72.1%), decreased size without necrosis in 11 patients (25.6%), and no change in one patient (2.3%). The mean volume reduction of the uteri after uterine artery embolization was 32.5% (from 321.7+/-142.9 to 216.7+/-130.1 cm(3)).ConclusionTranscatheter uterine artery embolization is an effective therapy for the treatment of symptomatic pure adenomyosis, and may be a valuable alternative to hysterectomy.

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Condition tags

dysmenorrheaendometriosisadenomyosis

MeSH descriptors

Embolization, Therapeutic Endometriosis Uterus Adult Arteries Catheterization Dysmenorrhea Dysmenorrhea Dysmenorrhea Embolization, Therapeutic Endometriosis Endometriosis Female Humans Magnetic Resonance Imaging Magnetic Resonance Imaging Menorrhagia Menorrhagia Menorrhagia Middle Aged

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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