Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis

Hisao Osada, Osada H, Silber S, Sherman J. Silber, Sherman Silber, Toshiyuki Kakinuma, Nagaishi M, Masaji Nagaishi, Keiichi Kato, Kato K, Osamu Kato, Kato O
Reproductive BioMedicine Online · 2010 · vol. 22(1) , pp. 94–99 · doi:10.1016/j.rbmo.2010.09.014 · PMID:21118751 · W2069169165
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This paper describes a surgical procedure designed to preserve the uterus for future pregnancy in patients experiencing extensive adenomyosis.

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Abstract

The treatment for severe adenomyosis has usually been hysterectomy, because there is no line of demarcation between diseased and normal tissue. Yet many such women wish to retain their uterus and some even wish to bear children. This report evaluates the efficacy of a new method of adenomyomectomy, where adenomyotic tissues are radically excised and the uterine wall is reconstructed by a triple-flap method, without overlapping suture lines, to prevent uterine rupture in subsequent pregnancies. This is a prospective case series followed for 10 years from June 1998 to August 2008 of 104 women with severe adenomyosis verified histologically and with magnetic resonance imaging. There was a dramatic reduction in both dysmenorrhoea and hypermenorrhoea and all patients returned to having normal menstrual cycles. Of 26 women who wished to conceive, 16 became pregnant, 14 (53.8%)went to term and delivered a healthy baby and there were no cases of uterine rupture. Adenomyosis symptoms recurred in only four out of 104 cases. The procedure thus resulted in a dramatic reduction in symptoms and allowed over half of women who wished to conceive to go to term without uterine rupture.

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Condition tags

dysmenorrheaendometriosisadenomyosis

MeSH descriptors

Endometrial Hyperplasia Endometriosis Infertility, Female Plastic Surgery Procedures Uterus Dysmenorrhea Dysmenorrhea Endometrial Hyperplasia Endometrial Hyperplasia Endometriosis Endometriosis Female Humans Infertility, Female Menorrhagia Menorrhagia Pregnancy Pregnancy Outcome Pregnancy Rate Recurrence

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (50)

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