Ultrasound-guided transcervical radiofrequency ablation for symptomatic uterine adenomyosis

Ning Hai, Hai N, Hou Q, Qingxiang Hou, Ding X, Ding Xiao-ping, XIAOPING DING, Dong X, Xiangping Dong, Jin M, Meijuan Jin
The British journal of radiology · 2016 · vol. 90(1069) , pp. 20160119 · doi:10.1259/bjr.20160119 · PMID:27792415 · PMC5605011 · W2540825440
article OA: closed CC0 ⤵ 26 in-corpus citations
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This study evaluated ultrasound-guided radiofrequency ablation in 87 women with symptomatic adenomyosis, finding significant reduction in uterus volume, dysmenorrhea, and symptom severity at 12 months post-procedure.

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Abstract

OBJECTIVE: To retrospectively evaluate the midterm outcomes of transvaginal ultrasound-guided radiofrequency ablation (RFA) for the treatment of symptomatic uterine adenomyosis. METHODS: 87 patients with symptomatic uterine adenomyosis, who met the inclusion criteria, were enrolled in our study from January 2013 to October 2015. All of the patients underwent transvaginal ultrasound-guided RFA and were followed up for 12 months. Assessment end points included uterus volume reduction rate, lesion regression rate, dysmenorrhoeal score, symptom severity score (SSS) and adverse events. RESULTS: In all 87 patients, 81 patients fulfilled the follow-up evaluations post-ablation. The mean uterine volume reduction rate was 35.8% at 1 month, 40.8% at 6 months and 41.2% at 12 months post-ablation. Dysmenorrhoea and SSS statistically significantly declined. Reintervention rate was 18.5%. Two patients developed intrauterine adhesion after ablation. No serious complications including penetration or burn injuries of the nearby organs were observed. CONCLUSION: Ultrasound-guided RFA might be a safe and effective minimally invasive alternative in the treatment of symptomatic adenomyosis. Advances in knowledge: This is the first study to evaluate the efficacy and safety of ultrasound-guided RFA for the treatment of adenomyosis to our knowledge. This is also the first study to provide various changes of intrauterine cavity after this treatment.

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Condition tags

dysmenorrheaadenomyosis

MeSH descriptors

Adenomyosis High-Intensity Focused Ultrasound Ablation Myometrium Patient Safety Adenomyosis Adenomyosis Adult Catheter Ablation Catheter Ablation Catheter Ablation China Cohort Studies Dysmenorrhea Dysmenorrhea Dysmenorrhea Female Follow-Up Studies High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation Humans

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