Medical treatment of a grossly enlarged adenomyotic uterus with the levonorgestrel-releasing intrauterine system
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This paper reports on the successful medical management of a significantly enlarged adenomyotic uterus using a levonorgestrel-releasing intrauterine system.
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Abstract
Adenomyosis is an important cause of menorrhagia. Besides hysterectomy, the treatment options for adenomyosis have been limited. Presented here is the successful treatment of adenomyosis in a woman presenting with menorrhagia, dysmenorrhea, and an enlarging uterus, for whom conservative therapy initiated with mefenamic acid was unsatisfactory. The patient had insertion of the levonorgestrel-releasing intrauterine system (LNG-IUS). A marked decrease in uterine size occurred within 12 months of insertion accompanied by resolution of the menorrhagia and dysmenorrhea. Thus, the LNG-IUS is a viable option and represents a real advance in the treatment of adenomyosis.
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Cited by (50)
- Adenomyosis-Induced Urinary Retention: Case Analysis and Clinical Implications 2024
- Suture fixation of the levonorgestrel-releasing intrauterine device with hysteroscope for the treatment of adenomyosis in patients at high risk of device expulsion 2023
- The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis 2023
- Progesterone Actions and Resistance in Gynecological Disorders 2022
- Benign gynecologic lesions 2021
- Endometriosis 2021
- Current and Prospective Treatment of Adenomyosis 2021
- Role of Hormones in Common Benign Uterine Lesions: Endometrial Polyps, Leiomyomas, and Adenomyosis 2020
- Benign Uterine Diseases 2019
- Effect of pretreatment with a levonorgestrel-releasing intrauterine system on IVF and vitrified-warmed embryo transfer outcomes in women with adenomyosis 2019
- High intensity focused ultrasound treatment of adenomyosis: a comparative study 2018
- Minimally invasive treatment of adenomyosis 2018
- The Incidence of Adenomyosis in Histerectomy Cases 2018
- Myomas and Adenomyosis: Impact on Reproductive Outcome 2017
- Die medikamentöse Therapie der Patientin mit Endometriose 2017
- Adenomyosis: a systematic review of medical treatment 2016
- Treatment strategies for pelvic pain associated with adenomyosis 2016
- Adenomiosis: tratamiento 2015
- Benign endikasyonlarla yapılan histerektomi materyallerinde adenomiyozis sıklığı ile preoperatif endometrial biyopsi ve pelvik semptomlarla ilişkisi 2015
- Adenomyosis: A Clinical Review of a Challenging Gynecologic Condition 2015
- Role of levonorgestrel-releasing intrauterine system in dysmenorrhea due to adenomyosis and the influence on ovarian function 2014
- Efficacy of combined levonorgestrel-releasing intrauterine system with gonadotropin-releasing hormone analog for the treatment of adenomyosis 2013
- Endometriosis 2012
- Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems 2012
- Effects of levonorgestrel-releasing intrauterine system and T380A intrauterine copper device on dysmenorrhea and days of bleeding in women with and without adenomyosis 2012
- Adenomyosis: review of the literature 2011
- Use of aromatase inhibitors in gynecology 2010
- Surgical options for pelvic pain 2010
- Insertion of the Mirena intrauterine system for treatment of adenomyosis-associated menorrhagia: a novel method 2010
- Surgical options for pelvic pain 2010
- Comparison of levonorgestrel intrauterine system versus hysterectomy on efficacy and quality of life in patients with adenomyosis 2010
- Efeitos do sistema intra-uterino de Levonorgestrel sobre marcadores de risco cardiovascular de pacientes com endometriose: estudo comparativo com o análogo do GnRH 2009
- Safety, efficacy and patient acceptability of the contraceptive and non-contraceptive uses of the LNG-IUS 2009
- Histerektomi Materyallerinde Adenomyozis Sıklığının Araştırılması 2009
- Intrauterine progestins, progesterone antagonists, and receptor modulators: a review of gynecologic applications 2009
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- Adenomyosis uteri: an update 2009
- Clinical effects of the levonorgestrel-releasing intrauterine device in patients with adenomyosis 2008
- Early results of magnetic resonance-guided focused ultrasound surgery of adenomyosis: analysis of 20 cases 2008
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- Laparoscopic excision of uterine adenomyomas 2007
- Hormonal treatments for adenomyosis 2007
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- Traitement de l'adénomyose 2007
- Endometriosis 2007
- Endometriosis and Adenomyosis 2007
- Local drug release systems in endometriosis 2007
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- Tratamiento de la adenomiosis 2007
- Medical and surgical management of adenomyosis 2006
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- europepmc
- last seen: 2026-10-14T06:08:39.101224+00:00
- openalex
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- pubmed
- last seen: 2026-10-08T20:59:14.592962+00:00
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