Intrauterine progestins, progesterone antagonists, and receptor modulators: a review of gynecologic applications

María I. Rodríguez, Maria Isabel Rodriguez, Meredith Warden, Warden M, Darney Pd, Philip D. Darney
American journal of obstetrics and gynecology · 2009 · vol. 202(5) , pp. 420–428 · doi:10.1016/j.ajog.2009.10.863 · PMID:20031112 · W1974224065
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This review examines the gynecologic applications of intrauterine progestins, progesterone antagonists, and selective progesterone receptor modulators.

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Abstract

Intrauterine progestins, progesterone receptor modulators, and antagonists have many important current and potential gynecologic applications. This article will describe the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. We will review the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, adenomyosis treatment, uterine fibroids, endometrial hyperplasia, and its concurrent use in women on hormone replacement therapy or tamoxifen.

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Condition tags

endometriosis

MeSH descriptors

Progestins Receptors, Progesterone Administration, Topical Endometriosis Endometriosis Female Humans Hysterectomy Hysterectomy Intrauterine Devices, Medicated Leiomyoma Leiomyoma Menorrhagia Menorrhagia Progestins Receptors, Progesterone Reproductive Medicine Uterine Neoplasms Uterine Neoplasms

Citation neighborhood

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References (78)

Cited by (5)

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License: CC0 · commercial use OK