Intrauterine progestins, progesterone antagonists, and receptor modulators: a review of gynecologic applications

María I. Rodríguez, Maria Isabel Rodriguez, Meredith Warden, Warden M, Darney Pd, Philip D. Darney
American journal of obstetrics and gynecology · 2009 · vol. 202(5) , pp. 420–428 · doi:10.1016/j.ajog.2009.10.863 · PMID:20031112 · W1974224065
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This review examines the gynecologic applications of intrauterine progestins, progesterone antagonists, and selective progesterone receptor modulators.

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Abstract

Intrauterine progestins, progesterone receptor modulators, and antagonists have many important current and potential gynecologic applications. This article will describe the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. We will review the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, adenomyosis treatment, uterine fibroids, endometrial hyperplasia, and its concurrent use in women on hormone replacement therapy or tamoxifen.

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Condition tags

endometriosis

MeSH descriptors

Progestins Receptors, Progesterone Administration, Topical Administration, Topical Endometriosis Endometriosis Endometriosis Female Female Humans Humans Hysterectomy Hysterectomy Hysterectomy Intrauterine Devices, Medicated Intrauterine Devices, Medicated Leiomyoma Leiomyoma Leiomyoma Menorrhagia

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (78)

Cited by (5)

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License: CC0 · commercial use OK