Insertion of the Mirena Intrauterine System for Treatment of Adenomyosis-Associated Menorrhagia: A Novel Method

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AI-generated summary by claude@2026-06, 2026-06-08

Yang's insertion method for the Mirena intrauterine system reduced expulsion rates in patients with adenomyosis-associated menorrhagia compared to the conventional method.

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Abstract

OBJECTIVE: Insertion of the levonorgestrel-releasing intrauterine system Mirena is difficult in women with adenomyosis, and the device is often subsequently expelled. We used a novel insertion technique (Yang's method) to overcome this problem. MATERIALS AND METHODS: This retrospective study enrolled 273 patients with adenomyosis who were receiving Mirena for treatment of menorrhagia and/or dysmenorrhea between 2001 and 2008. Clinical outcomes and expulsion rates were compared between patients treated using conventional insertion and those treated using Yang's insertion methods. RESULTS: Expulsion occurred in 25.3% of patients with the conventional method, compared with 10.2% of patients with Yang's method. Hemoglobin levels and dysmenorrhea improved greatly in both groups after Mirena insertion. CONCLUSION: Yang's insertion method for levonorgestrel-releasing intrauterine system is more reliable in some difficult cases, such as patients with severe adenomyosis. This method ensures correct positioning, thus reducing the risks of uterine perforation and/or expulsion.

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Condition tags

mesh:D004412mesh:D004715adenomyosisdysmenorrhea

MeSH descriptors

Endometriosis Intrauterine Devices, Medicated Menorrhagia Uterine Diseases Adult Anemia Anemia Anemia Contraceptive Agents, Female Contraceptive Agents, Female Dysmenorrhea Dysmenorrhea Dysmenorrhea Endometriosis Female Humans Intrauterine Device Expulsion Levonorgestrel Levonorgestrel Menorrhagia

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
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