Ming-Yih Wu

OBJECTIVE: Insertion of the levonorgestrel-releasing intrauterine system Mirena is difficult in women with adenomyosis, and the device is often subsequently expelled. We used a novel insertion technique (Yang's method) to overcome this prob…

ObjectiveTo investigate cell invasiveness and the production of matrix metalloproteinase-2 (MMP-2), MMP-9, tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2 in endometrial stromal cells (ESCs) of adenomyosis.DesignProspective stud…

BACKGROUND: The eutopic endometrium in a woman suffering from adenomyosis is known to be biologically different from that of healthy women. The aim of this study was to examine the apoptosis and proliferation of eutopic endometrium from wom…

ObjectiveTo examine changes in local cytokine production in the eutopic endometrium of adenomyosis after treatment with medroxyprogesterone acetate (MPA) and danazol.DesignProspective cohort study.SettingTertiary university hospital.Patient…

PROBLEM: To determine the effects of macrophage on endometrial stromal cells (ESCs) in women with adenomyosis. METHOD OF STUDY: Eutopic endometrium was obtained and separated into single ESC in 10 women with adenomyosis (study group) and 1…

BACKGROUND: Previous studies have shown that peritoneal macrophages from women with endometriosis produce excess nitric oxide (NO). This study was designed to quantify the amount of NO and determine the expression of endothelial (eNOS) and …

PROBLEM: To review the literature on the role of peritoneal cytokines in the pathogenesis and endometriosis-related infertility. METHODS OF STUDY: A MEDLINE search was conducted by the key words of cytokine and endometriosis in the English …